Muscle pain originates in any of the muscles in the body. The medical term for muscle pain is myalgia. Muscle pain may arise due to injury or overexertion, infections of the soft tissues, or inflammatory conditions. A number of conditions can be associated with generalized aches and pain, such as influenza, that are perceived to be muscle pain. Muscle pain can be localized to one muscle group or diffuse, involving multiple muscle groups. Muscle pain due to injury or overuse is most commonly localized to one area. Depending upon the cause, muscle pain can be mild or severe and debilitating. Muscle pain is the hallmark symptom of some chronic conditions like fibromyalgia. Related symptoms that can occur with muscle pain are tenderness, swelling, redness, or fever.
Kasper, D.L., et al., eds. Harrison's Principles of Internal Medicine, 19th Ed. United States: McGraw-Hill Education, 2015.
Main Article on Muscle Pain (Myalgia)
Causes of Muscle Pain (Myalgia)
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Chronic Fatigue Syndrome (CFS or SEID)
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Cold vs. Flu
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Dystonia disorders cause involuntary movements and prolonged muscle contraction, resulting in twisting body motions, tremor, and...
Fibromyalgia is a chronic pain condition characterized by symptoms such as fatigue, sleep disturbances, and tender points. Stress...
Influenza (flu) is a respiratory illness caused by a virus. Flu symptoms include fever, cough, sore throat, runny nose, headache,...
Heat cramps usually affect people who sweat a lot during strenuous activity or work in a hot, humid environment. Symptoms of heat...
Heat exhaustion is a milder form of heat-related illness that can develop after several days of exposure to high temperatures and...
Is the Ebola Virus Contagious?
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Lupus (Systemic Lupus Erythematosus or SLE)
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Muscle cramps are involuntarily and forcibly contracted muscles that do not relax. Extremely common, any muscles that have...
Polymyalgia rheumatica (PMR) is a disorder of the muscles and joints that causes pain and stiffness in the arms, neck, shoulders,...
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Rhabdomyolysis is a rapid deterioration and destruction of skeletal muscle. Some of the causes of rhabdomyolysis include:...
Rheumatoid Arthritis (RA)
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Rocky Mountain Spotted Fever (RMSF)
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Sprains and Strains
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Trichinosis Worm Infection
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Other Causes of Muscle Pain (Myalgia)
- Ciguatera Poisoning
- Electrolyte Imbalance
- Medication Side Effects
- Muscle Abscess
- Muscle Rupture
- Viral Infection
Examples of Medications for Muscle Pain (Myalgia)
- acetaminophen (Tylenol, Tylenol Arthritis Pain, Tylenol Ext, Little Fevers Children's Fever/Pain)
- Benzodiazepines vs. Cyclobenzaprine
- ibuprofen (Advil, Children's Advil/Motrin, Medipren, Motrin, Nuprin, PediaCare Fever, and others)
- naproxen (Aleve, Anaprox, Naprelan, Naprosyn)
- Nonsteroidal Antiinflammatory Drugs (NSAIDs)
- orphenadrine (Norflex)
- Oxycodone vs. Codeine