Reviewed on 8/5/2021

What Is Mylicon and How Does It Work?

Mylicon (simethicone) is an over-the-counter (OTC) product that relieves the discomfort of infant gas frequently caused by air swallowing or certain formulas or foods. Mylicon belongs to a class of medications called gastrointestinal agents, which are used to relieve gas.

Mylicon is also available under different brand names including Phazyme, Gas X Extra Strength, Gas X Softgels, Gas X Thin Strips, Children's Gas X Tongue Twisters Thin Strips, Gas X, PediaCare Infant's Gas Relief Drops, and St. Joseph Infant's Gas Relief.

Mylicon works by changing the surface tension of gas bubbles and causing the collapse of foam bubbles, thus allowing easier passage of gas and preventing gas pockets in the gastrointestinal tract of the patient.

Dosages of Mylicon

Each Dose of Mylicon Should Be Given As Follows:

Adult and pediatric doses:
  • 80 mg
  • 125 mg


  • 125 mg
  • 180 mg

Tablet, Chewable

  • 80 mg
  • 125 mg

Liquid, Oral

  • 20 mg per 0.3mL

Oral suspension

  • 20 mg per 0.3mL
  • 40 mg per 0.6mL

Strip, orally disintegrating

  • 40 mg
  • 62.5 mg


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What Are Side Effects Associated with Using Mylicon?

Common side effects and adverse effects of Mylicon include:  Loose stools

What Other Drugs Interact with Mylicon?

If your doctor has directed you to use this medication for a specific condition, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. A patient should not start, stop, or change the dosage of any medicine before checking with a doctor, health care provider or pharmacist first for more information.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use, and any medications used if this drug is to be administered to a baby. Keep a list with you to account for all your medications, and share the list with your doctor and pharmacist.

What Are Warnings and Precautions for Mylicon?


This medication contains simethicone. Do not take Mylicon if you are allergic to simethicone or any ingredients contained in this drug.

This product should be kept safe and out of reach of children. In case of overdose, get medical help or contact a Poison Control Center right away.


Hypersensitivity to simethicone.

Effects of Drug Abuse


Short-Term Effects


Long-Term Effects



Chewable tablets should be chewed thoroughly before swallowing; liquid-filled capsules should not be chewed.

Can cause false-negative gastric guaiac test.

Pregnancy and Lactation

Use with caution during pregnancy if benefits outweigh risks. Animal studies show sign of risk and human studies not available or neither animal nor human studies done. Mylicon is not absorbed systemically; it is not expected to be excreted in milk.

Disclaimer: Most OTC drugs are not reviewed and approved by FDA, however they may be marketed if they comply with applicable regulations and policies. FDA has not evaluated whether this product complies.

Medscape. Simethicone (OTC).
U.S. National Library of Medicine. DailyMed. Mylicon Infant Gas Relief.

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