Myrbetriq vs. Enablex

Are Myrbetriq and Enablex the Same Thing?

Myrbetriq (mirabegron) and Enablex (darifenacin) are used to treat overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency.

Myrbetriq and Enablex belong to different drug classes. Myrbetriq is a beta-3 adrenergic agonist and Enablex is an antispasmodic.

Side effects of Myrbetriq and Enablex that are similar include dry mouth, sore throat, diarrhea, constipation, headache, dizziness, blurred vision, stomach pain or upset, or nausea.

Side effects of Myrbetriq that are different from Enablex include increased blood pressure, inability to fully empty the bladder (urinary retention), sinus pain, bloating, memory issues, joint pain, or tired feeling.

Side effects of Enablex that are different from Myrbetriq include dry eyes, weakness, drowsiness, or fever, body aches, or other flu symptoms.

Myrbetriq may interact with metoprolol, desipramine, or digoxin.

Enablex may interact with other bladder or urinary medications, glycopyrrolate, flecainide, mepenzolate, thioridazine, HIV /AIDS medicines, antibiotics, antifungal medications, atropine, dimenhydrinate, methscopolamine, scopolamine, bronchodilators, irritable bowel medications, or antidepressants.

What Are Possible Side Effects of Myrbetriq?

Common side effects of Myrbetriq include:

  • drowsiness,
  • dizziness,
  • constipation,
  • nausea,
  • vomiting,
  • loss of appetite,
  • dry mouth, or
  • warmth or redness under the skin.

Tell your doctor if you have any serious side effects of Myrbetriq including:

  • increased blood pressure,
  • the inability to fully empty the bladder (urinary retention),
  • sinus pain,
  • dry mouth,
  • sore throat,
  • diarrhea,
  • constipation,
  • bloating,
  • memory issues,
  • headache,
  • joint pain,
  • dizziness,
  • blurred vision,
  • tired feeling,
  • stomach pain and,
  • nausea.

Tell your doctor if you experience serious side effects of Myrbetriq including

What Are Possible Side Effects of Enablex?

Common side effects of Enablex include:

  • dry mouth,
  • constipation,
  • nausea,
  • stomach pain or upset,
  • blurred vision,
  • dry eyes,
  • dizziness,
  • weakness,
  • diarrhea,
  • drowsiness,
  • headache, or
  • fever,
  • sore throat,
  • body aches, or
  • other flu symptoms.

Tell your doctor if you have serious side effects of Enablex including:

  • severe stomach or abdominal pain,
  • constipation for 3 or more days,
  • difficulty urinating,
  • signs of kidney infection (such as burning/painful/frequent urination, fever, pink or bloody urine), or
  • mental/mood changes (such as confusion, hallucinations).

What Is Myrbetriq?

Myrbetriq (mirabegron) is a beta-3 adrenergic agonist used to treat overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency.

What Is Enablex?

Enablex (darifenacin) is a urinary antispasmodic used to treat symptoms of overactive bladder, such as frequent or urgent urination, and incontinence (urine leakage).

SLIDESHOW

Urinary Incontinence in Women: Types, Causes, and Treatments for Bladder Control See Slideshow

What Drugs Interact With Myrbetriq?

Myrbetriq may interact with metoprolol, desipramine, or digoxin.

What Drugs Interact With Enablex?

Other bladder or urinary medications, glycopyrrolate, flecainide, mepenzolate, thioridazine, HIV /AIDS medicines, antibiotics, antifungal medications, atropine, benztropine, dimenhydrinate, methscopolamine, scopolamine, bronchodilators, irritable bowel medications, or antidepressants. Tell your doctor all medications you are taking. Enablex should be used only when prescribed during pregnancy. It is not known whether this drug passes into breast milk. Consult your doctor before breastfeeding.

How Should Myrbetriq Be Taken?

Myrbetriq is available as a 10 mg tablet and a solution (30 mg per ml) for intravenous (IV) or intramuscular (IM) administration. Myrbetriq solution is administered as a single 15- to 60-mg dose once every 6 hours not to exceed 60 or 120 mg a day. The recommended oral dose is one to two Myrbetriq tablets initially followed by one tablet every 4-6 hours, not to exceed 40 mg daily. Myrbetriq should not be used for more than 5 days.

How Should Enablex Be Taken?

The recommended starting dose of Enablex is 7.5 mg once daily. Based upon individual response, the dose may be increased to 15 mg once daily.

Disclaimer

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References

Astellas Pharma US, Inc. Myrbetriq Product Information.
https://www.myrbetriq.com
DailyMed. Enablex Product Information.
https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a712f252-16d9-47df-b2bf-6794228f3a88

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