Myrbetriq vs. Sanctura

Are Myrbetriq and Sanctura the Same Thing?

Myrbetriq (mirabegron) and Sanctura (trospium chloride) are used to treat overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency.

Myrbetriq and Sanctura belong to different drug classes. Myrbetriq is a beta-3 adrenergic agonist and Sanctura is a muscarinic antagonist.

Side effects of Myrbetriq and Sanctura that are similar include dry mouth, constipation, headache, dizziness, or blurred vision.

Side effects of Myrbetriq that are different from Sanctura include increased blood pressure, inability to fully empty the bladder (urinary retention), sinus pain, sore throat, diarrhea, bloating, memory issues, joint pain, tired feeling, stomach pain, or nausea.

Side effects of Sanctura that are different from Myrbetriq include dry throat, stomach upset, gas, dry eyes, or drowsiness.

Myrbetriq may interact with metoprolol, desipramine, or digoxin.

Sanctura may interact with atropine, dicyclomine, glycopyrrolate, hyoscyamine, mepenzolate, metformin, methscopolamine, morphine, procainamide, propantheline, scopolamine, tenofovir, or vancomycin.

What Are Possible Side Effects of Myrbetriq?

Common side effects of Myrbetriq include:

  • drowsiness,
  • dizziness,
  • constipation,
  • nausea,
  • vomiting,
  • loss of appetite,
  • dry mouth, or
  • warmth or redness under the skin.

Tell your doctor if you have any serious side effects of Myrbetriq including:

  • increased blood pressure,
  • the inability to fully empty the bladder (urinary retention),
  • sinus pain,
  • dry mouth,
  • sore throat,
  • diarrhea,
  • constipation,
  • bloating,
  • memory issues,
  • headache,
  • joint pain,
  • dizziness,
  • blurred vision,
  • tired feeling,
  • stomach pain and,
  • nausea.

Tell your doctor if you experience serious side effects of Myrbetriq including

What Are Possible Side Effects of Sanctura?

Common side effects of Sanctura include:

  • dry mouth or throat,
  • constipation,
  • stomach upset,
  • gas,
  • headache,
  • dry eyes,
  • dizziness,
  • blurred vision, or
  • drowsiness.

Tell your doctor if you have unlikely but serious side effects of Sanctura including:

  • eye pain,
  • difficulty urinating,
  • fast heartbeat, or
  • mental/mood changes (such as hallucinations, confusion).

What Is Myrbetriq?

Myrbetriq (mirabegron) is a beta-3 adrenergic agonist used to treat overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency.

What Is Sanctura?

Sanctura (trospium chloride) is a muscarinic antagonist, which relieves spasms of the bladder, used to treat overactive bladder and symptoms of urinary incontinence, frequency, and urgency.

SLIDESHOW

Urinary Incontinence in Women: Types, Causes, and Treatments for Bladder Control See Slideshow

What Drugs Interact With Myrbetriq?

Myrbetriq may interact with metoprolol, desipramine, or digoxin.

What Drugs Interact With Sanctura?

Sanctura may interact with atropine, dicyclomine, glycopyrrolate, hyoscyamine, mepenzolate, metformin, methscopolamine, morphine, procainamide, propantheline, scopolamine, tenofovir, or vancomycin. Tell your doctor all medications you use. During pregnancy, Sanctura should be used only when prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

How Should Myrbetriq Be Taken?

Myrbetriq is available as a 10 mg tablet and a solution (30 mg per ml) for intravenous (IV) or intramuscular (IM) administration. Myrbetriq solution is administered as a single 15- to 60-mg dose once every 6 hours not to exceed 60 or 120 mg a day. The recommended oral dose is one to two Myrbetriq tablets initially followed by one tablet every 4-6 hours, not to exceed 40 mg daily. Myrbetriq should not be used for more than 5 days.

How Should Sanctura Be Taken?

The recommended dose of Sanctura is 20 mg twice daily, taken at least one hour before meals or on an empty stomach.

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References

Astellas Pharma US, Inc. Myrbetriq Product Information.
https://www.myrbetriq.com
DailyMed Sanctura Product Information.
https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/021595s007lbl.pdf

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