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Myrbetriq vs. Vesicare

Reviewed on 3/21/2019

Are Myrbetriq and Vesicare the Same Thing?

Myrbetriq (mirabegron) and Vesicare (solifenacin) are used to treat overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency.

Myrbetriq and Vesicare belong to different drug classes. Myrbetriq is a beta-3 adrenergic agonist and Vesicare is a muscarinic receptor antagonist.

Side effects of Myrbetriq and Vesicare that are similar include dry mouth, sore throat, constipation, headache, dizziness, blurred vision, tired feeling, or nausea.

Side effects of Myrbetriq that are different from Vesicare include increased blood pressure, inability to fully empty the bladder (urinary retention), sinus pain, diarrhea, bloating, memory issues, joint pain, or stomach pain.

Side effects of Vesicare that are different from Myrbetriq include hoarse voice, dry eyes, loss of appetite, upset stomach, heartburn, drowsiness, weakness, fever, body aches, or flu symptoms.

Myrbetriq may interact with metoprolol, desipramine, or digoxin.

Vesicare may interact with azole antifungals, imatinib, nefazodone, St. John's wort, antibiotics, heart or blood pressure medicines, antiviral medicines to treat hepatitis or HIV/AIDS, seizure medicines, or tuberculosis medicines.

What Are Possible Side Effects of Myrbetriq?

Common side effects of Myrbetriq include:

  • drowsiness,
  • dizziness,
  • constipation,
  • nausea,
  • vomiting,
  • loss of appetite,
  • dry mouth, or
  • warmth or redness under the skin.

Tell your doctor if you have any serious side effects of Myrbetriq including:

  • increased blood pressure,
  • the inability to fully empty the bladder (urinary retention),
  • sinus pain,
  • dry mouth,
  • sore throat,
  • diarrhea,
  • constipation,
  • bloating,
  • memory issues,
  • headache,
  • joint pain,
  • dizziness,
  • blurred vision,
  • tired feeling,
  • stomach pain and,
  • nausea.

Tell your doctor if you experience serious side effects of Myrbetriq including

What Are Possible Side Effects of Vesicare?

Common side effects of Vesicare include:

  • constipation,
  • dry mouth,
  • hoarse voice,
  • dry eyes,
  • blurred vision,
  • nausea,
  • loss of appetite,
  • upset stomach,
  • heartburn,
  • headache,
  • dizziness,
  • drowsiness,
  • feeling tired,
  • weakness,
  • fever,
  • sore throat,
  • body aches, or
  • flu symptoms.

What Is Myrbetriq?

Myrbetriq (mirabegron) is a beta-3 adrenergic agonist used to treat overactive bladder (OAB) with symptoms of urge urinary incontinence, urgency, and urinary frequency.

What Is Vesicare?

Vesicare (solifenacin) is a muscarinic receptor antagonist that reduces muscle spasms of the bladder muscles and is used to treat the symptoms of overactive bladder such as incontinence, urinary frequency, and urgency.

SLIDESHOW

Urinary Incontinence in Women: Types, Causes, and Treatments for Bladder Control See Slideshow

What Drugs Interact With Myrbetriq?

Myrbetriq may interact with metoprolol, desipramine, or digoxin.

What Drugs Interact With Vesicare?

Tell your doctor all medications and supplements you use. Vesicare may be harmful to an unborn baby and should not be used by pregnant women. It is not known whether solifenacin passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

How Should Myrbetriq Be Taken?

Myrbetriq is available as a 10 mg tablet and a solution (30 mg per ml) for intravenous (IV) or intramuscular (IM) administration. Myrbetriq solution is administered as a single 15- to 60-mg dose once every 6 hours not to exceed 60 or 120 mg a day. The recommended oral dose is one to two Myrbetriq tablets initially followed by one tablet every 4-6 hours, not to exceed 40 mg daily. Myrbetriq should not be used for more than 5 days.

How Should Vesicare Be Taken?

The recommended dose of Vesicare is 5 mg administered as a tablet taken once daily. Vesicare may interact with azole antifungals.

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References

Astellas Pharma US, Inc. Myrbetriq Product Information.
https://www.myrbetriq.com
Astellas Pharma Inc. VESIcare Product Information.
https://www.vesicare.com/
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