Nabi HB

Last updated on RxList: 6/7/2018
Nabi HB Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 6/7/2018

Nabi-HB Hepatitis B Immune Globulin (Human) is made from human plasma used to prevent hepatitis B in people receiving a liver transplant, and in babies born to mothers infected with hepatitis B. Nabi-HB is also used to prevent hepatitis B in people who have been exposed to contaminated blood products, or through household or sexual contact with an infected person. Nabi-HB is not a vaccine and will not provide long-term protection from hepatitis B. For long-term protection you must receive a hepatitis B vaccine such as Engerix-B, Recombivax HB, or Twinrix. Nabi-HB is available in generic form. Common side effects of Nabi-HB include:

  • injection site reactions (redness, pain, or tenderness)
  • nausea
  • vomiting
  • upset stomach
  • diarrhea
  • fever
  • chills
  • dizziness
  • headache
  • back or joint pain
  • tremors or shaking, or t
  • iredness

An injection of Nabi-HB 0.06 mL/kg of body weight should be administered intramuscularly as soon as possible after exposure and within 24 hours, if possible. Nabi-HB may interact with other drugs. Tell your doctor all medications and supplements you use and all vaccines you recently received. During pregnancy, Nabi-HB should be used only if prescribed. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Nabi-HB Hepatitis B Immune Globulin (Human) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Digestive Disorders: Common Misconceptions See Slideshow
Nabi HB Consumer Information

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Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • fever, mouth sores, red or swollen gums;
  • a light-headed feeling, like you might pass out;
  • liver problems--upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
  • symptoms of fluid buildup around your lungs--chest pain, pain when you breathe, rapid heart rate, feeling light-headed or short of breath (especially when lying down); or
  • symptoms of a blood clot or stroke--sudden numbness or weakness (especially on one side of the body); chest pain, trouble breathing, rapid heart rate, coughing up blood; or pain, swelling, warmth, or redness in your arms or legs.

Common side effects may include:

  • nausea, vomiting, diarrhea, upset stomach;
  • back pain, tired feeling;
  • tremors, memory problems, agitation, vision problems;
  • cold symptoms such as stuffy nose, sneezing, sore throat;
  • mild rash; or
  • pain, redness, bruising, or tenderness where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Nabi HB (Hepatitis B Vaccine Recombinant)

Nabi HB Professional Information

SIDE EFFECTS

Fifty male and female volunteers received Nabi-HB, Hepatitis B Immune Globulin (Human), intramuscularly in pharmacokinetics trials20. The number of patients with reactions related to the administration of Nabi-HB included local reactions such as erythema 6 (12percent) and ache 2 (4percent) at the injection site, as well as systemic reactions such as headache 7 (14percent), myalgia 5 (10percent), malaise 3 (6percent), nausea 2 (4percent), and vomiting 1 (2percent). The majority (92percent) of reactions were reported as mild. The following adverse events were reported in the pharmacokinetics trials and were considered probably related to Nabi-HB: elevated alkaline phosphatase 2 (4percent), ecchymosis 1 (2percent), joint stiffness 1 (2percent), elevated AST 1 (2percent), decreased WBC 1 (2percent), and elevated creatinine 1 (2percent). All adverse events were mild in intensity. There were no serious adverse events. No anaphylactic reactions with Nabi-HB have been reported. However, these reactions, although rare, have been reported following the injection of human immune globulins23.

Read the entire FDA prescribing information for Nabi HB (Hepatitis B Vaccine Recombinant)

© Nabi HB Patient Information is supplied by Cerner Multum, Inc. and Nabi HB Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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