Slideshows Images Quizzes

Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. See additional information.


Last reviewed on RxList: 11/28/2018
Natroba Side Effects Center

Last reviewed on RxList 11/28/2018

Natroba (spinosad) Topical Suspension is a pediculicide used for the topical treatment of head lice infestation in patients six (6) months of age and older. Common side effects of Natroba include:

  • redness or irritation at the application site or in the eyes
  • application site dryness
  • application site skin peeling
  • hair loss, and
  • dry skin

Apply sufficient Natroba Topical Suspension to cover dry scalp, then apply to dry hair. Depending on hair length, apply up to a 120 mL (one bottle) dose to adequately cover scalp and hair. Leave on for 10 minutes, then thoroughly rinse off with warm water. If live lice are seen 7 days after the first treatment, a second treatment should be applied. Natroba may interact with other drugs. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Natroba. Spinosad, the active ingredient in Natroba, does not pass into breast milk. However, Natroba contains benzyl alcohol, which may be systemically absorbed through the skin, and pass into breast milk. A nursing woman may choose to pump and discard breast milk for 8 hours after use to avoid infant ingestion of benzyl alcohol. Consult your doctor before breastfeeding.

Our Natroba (spinosad) Topical Suspension Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Rosacea, Acne, Shingles, Covid-19 Rashes: Common Adult Skin Diseases See Slideshow
Natroba Professional Information

3 pharmacies near 20147 have coupons for Natroba (Spinosad) (Brand Names:Natroba for 120ML of 0.9%)

CVS Pharmacy
CVS Pharmacy

Est. Regular Price


with free coupon

View Coupon

Est. Regular Price


with free coupon

View Coupon
Harris Teeter Pharmacy
Harris Teeter Pharmacy

Est. Regular Price


with free coupon

View Coupon


Clinical Studies Experience

Because clinical studies are conducted under widely varying conditions, adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates in the clinical studies of another drug and may not reflect the rates observed in clinical practice.

NATROBA Topical Suspension was studied in two randomized, active-controlled trials (N=552) in subjects with head lice; the results are presented in Table 1.

Table 1: Selected Adverse Events Occurring in at least 1% of Subjects

Signs Spinosad
Permethrin 1%
Application site erythema
17 (3%)
31 (7%)
Ocular erythema
12 (2%)
15 (3%)
Application site irritation
5 (1%)
7 (2%)

Other less common reactions (less than 1% but more than 0.1%) were application site dryness, application site exfoliation, alopecia, and dry skin.

Systemic safety was not assessed in pediatric subjects under 6 months of age as laboratory parameters were not monitored in these controlled studies.

Read the entire FDA prescribing information for Natroba (Spinosad Topical Suspension)


Ringworm is caused by a fungus. See Answer
Related Resources for Natroba

Related Health

Related Drugs

© Natroba Patient Information is supplied by Cerner Multum, Inc. and Natroba Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors