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Necrotizing Fasciitis (cont.)

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What is the prognosis (outcome) for patients with necrotizing fasciitis? What are complications of necrotizing fasciitis?

Untreated necrotizing fasciitis has a poor prognosis; death or severe morbidity (for example, limb loss) is the frequent outcome. Even with appropriate treatment, the mortality (death) rate can be as high as 25%. Infection with MRSA and other multidrug-resistant organisms tends to have higher morbidity and mortality rates. Combined mortality and morbidity (for example, limb loss, scar formation, renal (kidney) failure, and sepsis) for all cases of necrotizing fasciitis has been reported as 70%-80%. Cases of Fournier's gangrene have reported as high as 75% mortality rates, while cases of Vibrio vulnificus-associated necrotizing fasciitis have about a 50% mortality rate. Fortunately, Vibrio vulnificus infection is relatively uncommon, but the incidence seems to be increasing. The U.S. Centers for Disease Control and Prevention (CDC), in 2007, made Vibrio vulnificus infection a reportable disease so the statistics on the incidence (frequency of occurrence) should be more easily obtained in the future.

The worst complication of this disease is rapid advancement that results in death. Other serious complications include tissue loss requiring surgical removal and amputation to limit disease, as well as sepsis, kidney failure, and extensive scarring.

What are some additional sources of information on necrotizing fasciitis?

"BBB - Aeromonas hydrophila," U.S. Food and Drug Administration

"Dermatologic Manifestations of Necrotizing Fasciitis,"


Maynor, Michael E. "Emergent Management of Necrotizing Fasciitis." Nov. 13, 2013. <>.

"Necrotizing Fasciitis (Flesh-Eating Bacteria)." Feb. 10, 2011. <>.

United States. Centers for Disease Control and Prevention. "Necrotizing Fasciitis: A Rare Disease, Especially for the Healthy." June 15, 2016. <>.

Medically Reviewed by a Doctor on 6/29/2016


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