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Nembutal

Last reviewed on RxList: 3/17/2021
Nembutal Side Effects Center

What Is Nembutal?

Nembutal (pentobarbital sodium) is a barbiturate that acts as a depressant, or sedative, used short-term to treat insomnia. Nembutal is also used as an emergency treatment for seizures, and to cause patients to fall asleep for surgery. Nembutal is available in generic form.

What Are Side Effects of Nembutal?

Common side effects of Nembutal include:

Seek medical attention immediately if you suffer from any serious side effects of Nembutal such as:

  • hallucinations,
  • weak or shallow breathing,
  • slow heart rate,
  • weak pulse, or
  • feeling like you might pass out.

Dosage for Nembutal

Dosage of Nembutal is determined by the patient's age, weight, and condition.

What Drugs, Substances, or Supplements Interact with Nembutal?

Nembutal may interact with other medications, including blood thinners, doxycycline, other seizure medications, MAO inhibitors, griseofulvin, birth control pills, hormone replacement estrogens, or steroids. Tell your doctor all medications you are taking.

Nembutal During Pregnancy and Breastfeeding

Do not use Nembutal if you are pregnant. It could harm a fetus. Nembutal may cause addiction or withdrawal symptoms in a newborn if the mother uses the medication during pregnancy. Nembutal can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breastfeeding. Nembutal may be habit-forming. Do not stop using Nembutal suddenly after using it long-term, or you could have withdrawal symptoms.

Additional Information

Our Nembutal Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Nembutal Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • confusion, agitation, hallucinations;
  • weak or shallow breathing;
  • slow heart rate, weak pulse; or
  • a light-headed feeling, like you might pass out.

Side effects such as confusion, depression, or excitement may be more likely in older adults and those who are ill or debilitated.

Common side effects may include:

  • drowsiness, dizziness;
  • loss of balance or coordination;
  • nausea, vomiting, constipation;
  • overactive reflexes;
  • sleep problems (insomnia), nightmares; or
  • feeling restless or excited (especially in children or older adults).

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Nembutal (Pentobarbital)

QUESTION

What is insomnia? See Answer
Nembutal Professional Information

SIDE EFFECTS

The following adverse reactions and their incidence were compiled from surveillance of thousands of hospitalized patients. Because such patients may be less aware of certain of the milder adverse effects of barbiturates, the incidence of these reactions may be somewhat higher in fully ambulatory patients.

More than 1 in 100 patients. The most common adverse reaction estimated to occur at a rate of 1 to 3 patients per 100 is: Nervous System: Somnolence.

Less than 1 in 100 patients. Adverse reactions estimated to occur at a rate of less than 1 in 100 patients listed below, grouped by organ system, and by decreasing order of occurrence are:

Nervous system: Agitation, confusion, hyperkinesia, ataxia, CNS depression, nightmares, nervousness, psychiatric disturbance, hallucinations, insomnia, anxiety, dizziness, thinking abnormality.

Respiratory system: Hypoventilation, apnea.

Cardiovascular system: Bradycardia, hypotension, syncope.

Digestive system: Nausea, vomiting, constipation.

Other reported reactions: Headache, injection site reactions, hypersensitivity reactions (angioedema, skin rashes, exfoliative dermatitis), fever, liver damage, megaloblastic anemia following chronic phenobarbital use.

To report SUSPECTED ADVERSE REACTIONS, contact Oak Pharmaceuticals, Inc. at 1-800-932-5676 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch.

Read the entire FDA prescribing information for Nembutal (Pentobarbital)

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© Nembutal Patient Information is supplied by Cerner Multum, Inc. and Nembutal Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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