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Last reviewed on RxList: 5/6/2008
Neo-Synephrine Side Effects Center

Last reviewed on RxList 12/2/2015

Neo-Synephrine (phenylephrine hydrochloride ophthalmic solution) is a vasoconstrictor (constricts the veins) and mydriatic (dilates the pupils), and the over-the-counter strength is used to relieve redness, burning, irritation, and dryness of the eye caused by wind, sun, and other minor irritants. Prescription-strength Neo-Synephrine is used to constrict blood vessels in the eye and to dilate (make bigger) the pupil for conditions such as glaucoma, before surgery, and before eye examinations. Neo-Synephrine is available in generic form. Common side effects of Neo-Synephrine include burning, stinging, pain, increased redness of the eye, tearing or blurred vision, headache, tremor, nausea, sweating, nervousness, dizziness, drowsiness, dryness in the nose, runny nose, and sneezing.

The dose of Neo-Synephrine depends on the condition being treated. Neo-Synephrine may interact with monoamine oxidase inhibitors (MAOIs) or beta-blockers. Talk to your doctor before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products. It is not known whether Neo-Synephrine will be harmful to a fetus. Talk to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether this medication passes into breast milk. Consult your doctor before breastfeeding.

Our Neo-Synephrine (phenylephrine hydrochloride ophthalmic solution) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Neo-Synephrine Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Although the risk of serious side effects is low when phenylephrine ophthalmic is used in the eyes, side effects can occur if the medicine is absorbed into your bloodstream. Stop using phenylephrine ophthalmic and call your doctor at once if you have:

  • fast or irregular heart rate;
  • sweating, tremors;
  • pale skin, light-headed feeling;
  • severe headache, buzzing in your ears, anxiety, shortness of breath; or
  • chest pain or pressure, pain spreading to your jaw or shoulder.

Less serious side effects may be more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Neo-Synephrine (Phenylephrine Hydrochloride Ophthalmic Solution)


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Neo-Synephrine Professional Information


No information provided.

Read the entire FDA prescribing information for Neo-Synephrine (Phenylephrine Hydrochloride Ophthalmic Solution)


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© Neo-Synephrine Patient Information is supplied by Cerner Multum, Inc. and Neo-Synephrine Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.


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