Last updated on RxList: 2/24/2009
Neodecadron Side Effects Center

Last reviewed on RxList 5/26/2016

Neodecadron (neomycin sulfate-dexamethasone sodium phosphate) Sterile Ophthalmic Solution is a topical corticosteroid-antibiotic used to treat bacterial infections of the eyes. The brand name Neodecadron is discontinued, but generic versions may be available. Serious side effects are not expected with Neodecadron (neomycin sulfate-dexamethasone sodium phosphate). Mild side effects of Neodecadron include:

  • some eye reactions when drops are instilled (burning, stinging, irritation, itching, redness, blurred vision)
  • eyelid itching
  • eyelid swelling, or
  • sensitivity to light

Instill one or two drops of Neodecadron Ophthalmic Solution into the conjunctival sac every hour during the day and every two hours during the night as initial therapy. When a favorable response is observed, reduce dosage to one drop every four hours. Neodecadron may interact with other eye medications, or oral steroid medications. Tell your doctor all medications and supplements you use. It is unknown if Neodecadron will harm a fetus. Do not use this medication without first talking to your doctor if you are pregnant. It is unknown if this drug passes into breast milk. Consult your doctor before breastfeeding.

Our Neodecadron (neomycin sulfate-dexamethasone sodium phosphate) Sterile Ophthalmic Solution Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Neodecadron Consumer Information

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

  • hearing problems, ringing in your ears, or a feeling of fullness in the ears;
  • spinning sensation, nausea, feeling like you might pass out;
  • loss of balance or coordination, trouble walking;
  • numbness or tingly feeling under your skin;
  • muscle twitching, seizure (convulsions);
  • urinating less than usual or not at all;
  • drowsiness, confusion, mood changes, increased thirst, loss of appetite, nausea and vomiting;
  • swelling, weight gain, feeling short of breath;
  • weak or shallow breathing; or
  • severe stomach cramps, diarrhea that is watery or bloody.

Less serious side effects may include:

  • mild nausea, vomiting; or
  • mild diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Neodecadron (Neomycin and Dexamethasone)


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Neodecadron Professional Information


Adverse reactions have occurred with corticosteroid/anti-infective combination drugs which can be attributed to the corticosteroid component, the anti-infective component, the combination, or any other component of the product. Exact incidence figures are not available since no denominator of treated patients is available.

Reactions occurring most often from the presence of the anti-infective ingredient are allergic sensitizations. The reactions due to the corticosteroid component in decreasing order of frequency are: elevation of intraocular pressure (IOP) with possible development of glaucoma, and infrequent optic nerve damage; posterior subcapsular cataract formation; and delayed wound healing.

Secondary Infection

The development of secondary infection has occurred after use of combinations containing corticosteroids and antimicrobials. Fungal and viral infections of the cornea are particularly prone to develop coincidentally with long-term applications of a corticosteroid. The possibility of fungal invasion must be considered in any persistent corneal ulceration where corticosteroid treatment has been used.

Read the entire FDA prescribing information for Neodecadron (Neomycin and Dexamethasone)

© Neodecadron Patient Information is supplied by Cerner Multum, Inc. and Neodecadron Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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