How Do Neurologic Interleukin Inhibitors Work?

Interleukin inhibitors are drugs used for the treatment of neuromyelitis optica spectrum disorder (NMOSD).

NMOSD is a chronic disorder of the brain and spinal cord, characterized by inflammation of the optic nerve (optic neuritis) and spinal cord (myelitis). NMOSD is thought to be triggered by a protein cytokine interleukin 6 (IL-6), which usually helps the body regulate immune responses. In rare conditions, cytokine IL-6 can trigger an inflammation cascade, leading to damage and disability in people with NMOSD.

Interleukin inhibitors target IL-6 receptors and inhibit them, preventing an inflammation cascade.

Interleukin inhibitors are used to prevent an inflammation cascade, which could lead to damage and disability in people with neuromyelitis optica spectrum disorder.

Some of the side effects of interleukin inhibitors include:

• Headache
• Rash
• Pain in the legs
• Upper respiratory tract infection
• Joint pain
• Fatigue
• Nausea
• Gastritis
• Itching
• Depression

The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.

Generic and brand names of interleukin inhibitors include:

• Enspryng
• Satralizumab
• Satralizumab-mwge