Nicotine Lozenge

Reviewed on 8/9/2021

What Is Nicotine Lozenge Used For and How Does it Work?

Nicotine Lozenge is an aid used to help smokers quit smoking. It is available over-the-counter (OTC).

Nicotine Lozenge is available under the following different brand names: Nicorette Lozenge and Nicorette Mini Lozenge.

Dosages of Nicotine Lozenge


  • 2 mg
  • 4 mg

Dosage Considerations – Should be Given as Follows:

Smoking Cessation

  • Weeks 1-6: 1 lozenge every 1-2 hours
  • Weeks 7-9: 1 lozenge every 2-4 hours
  • Weeks 10-12: 1 lozenge every 4-8 hours
  • Do not exceed more than 5 lozenges/6 hours
  • Do not exceed more than 20 lozenges/day
  • First cigarette smoked more than 30 minutes after awakening: Initiate with 2 mg
  • First cigarette smoked within 30 minutes of awakening: Initiate with 4 mg

Safety and efficacy not established for pediatric patients.


How to Quit Smoking: 13 Tips to End Addiction See Slideshow

What Are Side Effects Associated with Using Nicotine Lozenge?

Side effects of Nicotine Lozenge include:

  • Increased blood pressure
  • Fast heart rate
  • Dizziness
  • Insomnia
  • Irritability
  • Weight loss
  • Heartburn/indigestion
  • Hiccups
  • Increased salivation
  • Indigestion
  • Headache
  • Nausea
  • Vomiting
  • Cough

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

What Other Drugs Interact with Nicotine Lozenge?

If your doctor has directed you to use this medication, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider or pharmacist first.

Nicotine Lozenge has no listed interactions with other drugs.

This document does not contain all possible interactions. Therefore, before using this product, tell your doctor or pharmacist of all the products you use. Keep a list of all your medications with you, and share the list with your doctor and pharmacist. Check with your physician if you have health questions or concerns.

What Are Warnings and Precautions for Nicotine Lozenge?


This medication contains nicotine lozenge. Do not take Nicorette Lozenge or Nicorette Mini Lozenge if you are allergic to nicotine lozenge or any ingredients contained in this drug.

Keep out of reach of children. In case of overdose, get medical help or contact a Poison Control Center immediately.


Effects of Drug Abuse

No information available.

Short-Term Effects

  • See "What Are Side Effects Associated with Using Nicotine Lozenge?"

Long-Term Effects

  • See "What Are Side Effects Associated with Using Nicotine Lozenge?"


Pregnancy and Lactation

Use nicotine lozenge during pregnancy in LIFE-THREATENING emergencies when no safer drug is available. There is positive evidence of human fetal risk. Tobacco smoke is known to cause low birth weight, spontaneous abortion, increased perinatal mortality, decreased placental perfusion; however, nicotine replacement is believed to be safer during pregnancy than smoking.

Nicotine and its metabolite (cotinine) pass into breast milk up to hour after maternal smoking. The risk of exposure of infants to secondhand smoke may be more detrimental than nicotine replacement. Nicotine may increase infant heart rate.

Pregnant or breastfeeding patients should seek advice of their health professional before using over-the-counter (OTC) drugs.


What is the average weight gain for those who quit smoking? See Answer
Medscsape. Nicotine Lozenge.

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