Last updated on RxList: 6/22/2016
NitroMist Side Effects Center

Last reviewed on RxList 8/18/2015

NitroMist (nitroglycerin) is a nitrate, which is a vasodilator, used to treat or prevent attacks of chest pain (angina). Common side effects of NitroMist include: 

At the onset of an attack, a dose of one or two metered sprays of NitroMist should be administered on or under the tongue. A spray may be repeated approximately every 5 minutes as needed. No more than 3 metered sprays are recommended within a 15-minute period. NitroMist may interact with alcohol, alteplase, aspirin or heparin, bladder or urinary medications, blood pressure medications, bronchodilators, dihydroergotamine or ergotamine, antidepressants, beta-blockers, calcium channel blockers, irritable bowel medications, any medication that causes dry mouth, or medicines to treat psychiatric disorders. Tell your doctor all medications and supplements you use. It is unknown if NitroMist will harm a fetus. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

Our NitroMist (nitroglycerin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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NitroMist Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives, sweating, pale skin; nausea, vomiting; feeling weak or light-headed; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe or throbbing headaches that do not become less severe with continued use of nitroglycerin;
  • pounding heartbeats or fluttering in your chest;
  • slow heart rate;
  • a light-headed feeling, like you might pass out;
  • blurred vision or dry mouth; or
  • heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating.

Nitroglycerin can cause severe headaches that should become less severe as you continue to use the medicine.

Common side effects may include:

  • flushing (sudden warmth, redness, or tingly feeling);
  • feeling light-headed, fainting;
  • headache, dizziness; or
  • numbness, tingling, burning pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for NitroMist (Nitroglycerin Lingual Aerosol)


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NitroMist Professional Information


Headache, which may be severe and persistent, may occur immediately after nitroglycerin use.

Flushing, drug rash and exfoliative dermatitis have been reported in patients receiving nitrate therapy.

Postural hypotension, as manifest by vertigo, weakness, palpitation, and other symptoms, may develop occasionally, particularly in erect, immobile patients. Marked sensitivity to the hypotensive effects of nitrates (manifested by nausea, vomiting, weakness, diaphoresis, pallor, and collapse) may occur at therapeutic doses.

Syncope due to nitrate vasodilatation has been reported.

Read the entire FDA prescribing information for NitroMist (Nitroglycerin Lingual Aerosol)


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© NitroMist Patient Information is supplied by Cerner Multum, Inc. and NitroMist Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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