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Last reviewed on RxList: 8/12/2020
Nitrostat Side Effects Center

What Is Nitrostat?

Nitrostat (nitroglycerin) Sublingual Tablets are nitrates used to treat or prevent attacks of chest pain (angina). Nitrostat is available in generic form.

What Are Side Effects of Nitrostat?

Common side effects of Nitrostat include:

Other side effects of Nitrostat include:

  • mild burning or tingling with the tablet in your mouth, and
  • flushing (warmth, redness, or tingly feeling under your skin).

Tell your doctor if you experience unlikely but serious side effects of Nitrostat including:

  • fainting, or
  • fast/irregular/pounding heartbeat.

Dosage for Nitrostat

The dose of Nitrostat is one tablet dissolved under the tongue or in the buccal (cheek) pouch at the first sign of an acute anginal attack. The dose may be repeated approximately every 5 minutes until relief is obtained. If pain persists after 3 tablets in 15-minutes, or if the pain is different than typically experienced, prompt medical attention is recommended.

What Drugs, Substances, or Supplements Interact with Nitrostat?

Nitrostat may interact with alteplase, aspirin or heparin, bladder or urinary medications, blood pressure medication, bronchodilators, dihydroergotamine or ergotamine, erectile dysfunction medications, antidepressants, beta-blockers, calcium channel blockers, irritable bowel medications, medication that causes dry mouth, or medicines to treat psychiatric disorders. Tell your doctor all medications you use.

Nitrostat During Pregnancy and Breastfeeding

During pregnancy, Nitrostat should be used only when prescribed. It is not known if this drug passes into breast milk or if it may harm a nursing infant. Consult your doctor before breast-feeding.

Additional Information

Our Nitrostat (nitroglycerin) (nitroglycerin) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Nitrostat Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • severe or throbbing headaches that do not become less severe with continued use of nitroglycerin;
  • pounding heartbeats or fluttering in your chest;
  • slow heart rate;
  • a light-headed feeling, like you might pass out;
  • blurred vision or dry mouth; or
  • heart attack symptoms--chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating.

Nitroglycerin can cause severe headaches. These headaches may gradually become less severe as you continue to use nitroglycerin. Do not stop taking this medicine. Ask your doctor before using any headache pain medication.

Common side effects may include:

  • headache, dizziness; or
  • numbness, tingling, burning pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Nitrostat (Nitroglycerin)


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Nitrostat Professional Information


The following adverse reactions are discussed in more detail elsewhere in the label:

Vertigo, dizziness, weakness, palpitation, and other manifestations of postural hypotension may develop occasionally, particularly in erect, immobile patients. Marked sensitivity to the hypotensive effects of nitrates (manifested by nausea, vomiting, weakness, diaphoresis, pallor, and collapse) may occur at therapeutic doses. Syncope due to nitrate vasodilatation has been reported.

Flushing, drug rash, and exfoliative dermatitis have been reported in patients receiving nitrate therapy.

Read the entire FDA prescribing information for Nitrostat (Nitroglycerin)


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Related Resources for Nitrostat

Read the Nitrostat User Reviews »

© Nitrostat Patient Information is supplied by Cerner Multum, Inc. and Nitrostat Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.


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