Nizoral vs. Hydrocortisone

Are Nizoral and Hydrocortisone the Same Thing?

Nizoral (ketoconazole) is an antifungal indicated for the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.

Hydrocortisone (hydrocortisone) Cream 2.5% is a topical (for the skin) steroid used to treat inflammation of the skin caused by a number of conditions such as allergic reactions, eczema, or psoriasis.

Nizoral and hydrocortisone belong to different drug classes. Nizoral is an antifungal medication and hydrocortisone is a corticosteroid.

Side effects of Nizoral and hydrocortisone that are similar include nausea, skin itching, headache, and dizziness.

Side effects of Nizoral that are different from hydrocortisone include vomiting, stomach pain, skin rash, breast swelling, impotence, or loss of interest in sex.

Side effects of hydrocortisone that are different from Nizoral include skin redness/burning/peeling, thinning of your skin, blistering skin, stretch marks, heartburn, menstrual period changes, trouble sleeping (insomnia), increased sweating, or acne.

Nizoral may interact with acetaminophen, cyclosporine, clopidogrel, digoxin, tacrolimus, loratadine, methylprednisolone, phenytoin, rifampin, oral diabetes medications, sedatives, blood thinners, cancer medications, birth control pills or hormone replacement therapy, methotrexate, cholesterol medications, or medications to treat HIV/AIDS.

Hydrocortisone may interact with skin products that can cause irritation, such as harsh soaps, shampoos, hair coloring or permanent chemicals, hair removers or waxes, or skin products with alcohol, spices, astringents, or lime.

What Are Possible Side Effects of Nizoral?

Common side effects of Nizoral include:

  • nausea,
  • vomiting,
  • stomach pain,
  • itching or skin rash,
  • headache,
  • dizziness,
  • breast swelling,
  • impotence, or
  • loss of interest in sex.

Tell your doctor if you have serious side effects of Nizoral including:

What Are Possible Side Effects of Hydrocortisone?

Common side effects of Hydrocortisone include:

  • skin redness/burning/itching/peeling,
  • thinning of your skin,
  • blistering skin,
  • stretch marks,
  • nausea,
  • heartburn,
  • headache,
  • dizziness,
  • menstrual period changes,
  • trouble sleeping (insomnia),
  • increased sweating, or
  • acne.

Tell your doctor if you have any serious side effects of Hydrocortisone Cream including blurred vision, or seeing halos around lights, uneven heartbeats, weight gain, puffiness in your face, or feeling tired.

What Is Nizoral?

Nizoral (ketoconazole) is an antifungal agent indicated for the treatment of the following systemic fungal infections: candidiasis, chronic mucocutaneous candidiasis, oral thrush, candiduria, blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.

What Is Hydrocortisone?

Hydrocortisone (hydrocortisone) Cream 2.5% is a topical (for the skin) steroid used to treat inflammation of the skin caused by a number of conditions such as allergic reactions, eczema, or psoriasis.

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What Drugs Interact With Nizoral?

Nizoral may interact with acetaminophen, cyclosporine, clopidogrel, digoxin, tacrolimus, loratadine, methylprednisolone, phenytoin, rifampin, oral diabetes medications, sedatives, blood thinners, cancer medications, birth control pills or hormone replacement therapy, methotrexate, cholesterol medications, or medications to treat HIV or AIDS. Tell your doctor all medications and supplements you use.

What Drugs Interact With Hydrocortisone?

It is not likely other drugs you take orally or inject will have an effect on topically applied hydrocortisone. But many drugs can interact with each other. Tell your doctor all prescription and over-the-counter medications and supplements you use. During pregnancy, hydrocortisone should be used only when prescribed. Infants born to mothers who have been using this medication for an extended period of time may have hormone problems.

How Should Nizoral Be Taken?

The recommended adult starting dose of Nizoral tablets is a single daily administration of 200 mg (one tablet).

How Should Hydrocortisone Be Taken?

Dose and administration: Apply hydrocortisone cream to the affected area as a thin film 2 to 4 times daily depending on the severity of the condition.

QUESTION

Eczema (also atopic eczema or atopic dermatitis) is a general medical term for many types of skin inflammation. See Answer
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References
SOURCE:

FDA. Nizoral Product Information

https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/019927s032lbl.pdf

DailyMed. Hydrocortisone Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5f6acc2b-7a6e-7f98-e053-2991aa0a46e7

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