HOW DO NMDA ANTAGONISTS WORK?
NMDA receptor allows the binding of the excitatory neurotransmitter glutamate to its site. When glutamate attaches to the NMDA receptor, it releases calcium into the nerve cells that is essential for the learning process and memory.
When the glutamate level increases in the brain, it causes excess release of calcium, which can damage the nerve cells.
NMDA antagonists bind to NMDA receptors and prevent the binding of glutamate, thereby preventing the release of calcium into the nerve cells.
HOW ARE NMDA ANTAGONISTS USED?
NMDA antagonists are prescribed to treat the following conditions:
WHAT ARE SIDE EFFECTS OF NMDA ANTAGONISTS?
NMDA antagonists can cause the following side effects:
- Somnolence (daytime sleepiness)
- Syncope (blackout)
- Dyspnea (shortness of breath)
The information contained herein is not intended to cover all possible side effects, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Check with your doctor or pharmacist to make sure these drugs do not cause any harm when you take them along with other medicines. Never stop taking your medication and never change your dose or frequency without consulting your doctor.