Last updated on RxList: 6/8/2021
Norflex Side Effects Center

What Is Norflex?

Norflex (orphenadrine citrate) is a muscle relaxant indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute painful musculoskeletal conditions. The brand name Norflex is discontinued. Orphenadrine citrate is available as a generic.

What Are Side Effects of Norflex?

Side effects of Norflex include:

Dosage for Norflex

The adult dose of Norflex tablets is two tablets per day; one in the morning and one in the evening. The adult dose of Norflex injection is one 2 mL ampul (60 mg) intravenously or intramuscularly; may be repeated every 12 hours. Relief may be maintained by 1 Norflex Extended-Release Tablet twice daily.

Norflex In Children

Safety and effectiveness of Norflex in pediatric patients have not been established.

What Drugs, Substances, or Supplements Interact with Norflex?

Norflex may interact with other medicines.

Tell your doctor all medications and supplements you use.

Norflex During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Norflex; it is unknown how it might affect a fetus. Consult your doctor before breastfeeding.

Additional Information

Our Drug name (generic) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Back Pain: 16 Back Pain Truths and Myths See Slideshow
Norflex Consumer Information

3 pharmacies near 20147 have coupons for Norflex (Brand Names:Norflex for 100MG)


Est. Regular Price


with free coupon

View Coupon

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using orphenadrine and call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • painful or difficult urination;
  • little or no urination;
  • confusion, anxiety, agitation, tremors, hallucinations; or
  • pounding heartbeats or fluttering in your chest.

Common side effects may include:

  • dizziness, drowsiness, weakness;
  • nausea, vomiting;
  • dry mouth; or
  • constipation.

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Norflex (Orphenadrine Injection)


Nearly everyone has low back pain at some time during their life. See Answer
Norflex Professional Information


Adverse reactions of orphenadrine are mainly due to the mild anti-cholinergic action of orphenadrine, and are usually associated with higher dosage. Dryness of the mouth is usually the first adverse effect to appear. When the daily dose is increased, possible adverse effects include: tachycardia, palpitation, urinary hesitancy or retention, blurred vision, dilatation of pupils, increased ocular tension, weakness, nausea, vomiting, headache, dizziness, constipation, drowsiness, hypersensitivity reactions, pruritus, hallucinations, agitation, tremor, gastric irritation, and rarely urticaria and other dermatoses. Infrequently, an elderly patient may experience some degree of mental confusion. These adverse reactions can usually be eliminated by reduction in dosage. Very rare cases of aplastic anemia associated with the use of orphenadrine tablets have been reported. No causal relationship has been established.

Rare instances of anaphylactic reaction have been reported associated with the intramuscular injection of Norflex (orphenadrine) Injection.

Drug Abuse And Dependence

Orphenadrine has been chronically abused for its euphoric effects. The mood elevating effects may occur at therapeutic doses of orphenadrine.

Read the entire FDA prescribing information for Norflex (Orphenadrine Injection)

© Norflex Patient Information is supplied by Cerner Multum, Inc. and Norflex Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

Health Solutions From Our Sponsors