Norketamine is the major metabolite (metabolic product) of the drug ketamine. Ketamine is a drug that is used as a treatment for depression or severe mental health conditions, although it is often misused recreationally. Norketamine is formed in the body after ketamine is taken.
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References
Jameson, J. Larry, et al. Harrison's Principles of Internal Medicine, 20th Ed. New York: McGraw-Hill Education, 2018.