Angelica Tree, Clavalier, Clavalier d'Amérique, Clavalier à Feuilles de Frêne, Clavalier Frêne, Frêne Épineux, Frêne Épineux du Nord, Fresno Espinoso Americano, Pepper Wood, Prickly Ash, Toothache Bark, Xanthoxylum, Yellow Wood, Zanthoxylum, Zanthoxylum americanum.
Northern prickly ash is a plant. The bark and berry are used to make medicine. Be careful not to confuse northern prickly ash with ash or southern prickly ash.
People take northern prickly ash for blood circulation problems and resulting conditions including leg pain (intermittent claudication) and Raynaud's syndrome. It is also used for joint pain, cramps, low blood pressure, fever, swelling (inflammation), toothache, sores, ulcers, and cancer (as an ingredient in Hoxsey cure).
Some people use northern prickly ash as a tonic, as a stimulant, and for “sweating out a fever.”
In manufacturing, northern prickly ash is used as a flavoring in foods and beverages.
How does it work?
It is not known how northern prickly ash might work.
Insufficient Evidence to Rate Effectiveness for...
- Joint pain.
- Circulation problems.
- Low blood pressure.
- Use as a tonic.
- Use as a stimulant.
- Other conditions.
Natural Medicines Comprehensive Database rates effectiveness based on scientific evidence according to the following scale: Effective, Likely Effective, Possibly Effective, Possibly Ineffective, Likely Ineffective, and Insufficient Evidence to Rate (detailed description of each of the ratings).
It's also wise to avoid northern prickly ash if you are breast-feeding. Not enough is known about its possible effects on nursing babies.
Stomach or intestinal problems including ulcers, Crohn's disease, irritable bowel syndrome, infections, or other digestive tract conditions: Northern prickly ash can stimulate digestive juices and cause irritation. This can make stomach and intestinal problems worse. Do not use northern prickly ash if you have any of these conditions.
AntacidsInteraction Rating: Minor Be cautious with this combination.Talk with your health provider.
Antacids are used to decrease stomach acid. Northern prickly ash may increase stomach acid. By increasing stomach acid, northern prickly ash might decrease the effectiveness of antacids.
Some antacids include calcium carbonate (Tums, others), dihydroxyaluminum sodium carbonate (Rolaids, others), magaldrate (Riopan), magnesium sulfate (Bilagog), aluminum hydroxide (Amphojel), and others.
Medications that decrease stomach acid (H2-blockers)Interaction Rating: Minor Be cautious with this combination.Talk with your health provider.
Northern prickly ash might increase stomach acid. By increasing stomach acid, northern prickly ash might decrease the effectiveness of some medications that decrease stomach acid, called H2-blockers.
Medications that decrease stomach acid (Proton pump inhibitors)Interaction Rating: Minor Be cautious with this combination.Talk with your health provider.
Northern prickly ash might increase stomach acid. By increasing stomach acid, northern prickly ash might decrease the effectiveness of medications that are used to decrease stomach acid, called proton pump inhibitors.
The appropriate dose of northern prickly ash depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for northern prickly ash. Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Health Solutions From Our Sponsors
Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.