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Nortriptyline Hydrochloride Oral Solution

Last reviewed on RxList: 1/30/2017
Nortriptyline Hydrochloride Oral Solution Side Effects Center

Last reviewed on RxList 5/20/2016

Nortriptyline Hydrochloride Oral Solution is an antidepressant used to relieve symptoms of depression. Nortriptyline hydrochloride oral solution is available in generic form. Common side effects of nortriptyline hydrochloride oral solution include:

Antidepressants such as nortriptyline hydrochloride oral solution increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults. Tell your doctor if you have worsening depression or thoughts of suicide while taking nortriptyline hydrochloride oral solution.

The usual adult dose of nortriptyline hydrochloride is 25 mg 3 or 4 times daily; dosage should begin at a low level and be increased as required. Nortriptyline hydrochloride may interact with cimetidine, fluoxetine hydrochloride, anticholinergic drugs, sympathomimetic drugs, other antidepressants, phenothiazines, carbamazepine, antiarrhythmics, or quinidine. Tell your doctor all medications and supplements you use. During pregnancy, nortriptyline hydrochloride should be used only if prescribed. Consult your doctor before breastfeeding.

Our Nortriptyline Hydrochloride Oral Solution Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


Depression is a(n) __________ . See Answer
Nortriptyline Hydrochloride Oral Solution Professional Information


NOTE: Included in the following list are a few adverse reactions that have not been reported with this specific drug. However, the pharmacologic similarities among the tricyclic antidepressant drugs require that each of these reactions be considered when nortriptyline is administered.

Cardiovascular--Hypotension, hypertension, tachycardia, palpitation, myocardial infarction, arrhythmias, heart block, stroke.

Psychiatric--Confusional states (especially in the elderly), with hallucinations, disorientation, delusions; anxiety, restlessness, agitation; insomnia, panic, nightmares; hypomania; exacerbation of psychosis.

Neurologic--Numbness, tingling, paresthesias of extremities; incoordination, ataxia, tremors; peripheral neuropathy; extrapyramidal symptoms; seizures, alteration of EEG patterns; tinnitus.

Anticholinergic--Dry mouth and, rarely, associated sublingual adenitis or gingivitis; blurred vision, disturbance of accommodation, mydriasis; constipation, paralytic ileus; urinary retention, delayed micturition, dilation of the urinary tract.

Allergic--Skin rash, petechiae, urticaria, itching, photosensitization (avoid excessive exposure to sunlight); edema (general or of face and tongue), drug fever, cross-sensitivity with other tricyclic drugs.

Hematologic--Bone-marrow depression, including agranulocytosis; aplastic anemia; eosinophilia; purpura; thrombocytopenia.

Gastrointestinal--Nausea and vomiting, anorexia, epigastric distress, diarrhea; peculiar taste, stomatitis, abdominal cramps, black tongue, constipation, paralytic ileus.

Endocrine--Gynecomastia in the male; breast enlargement and galactorrhea in the female; increased or decreased libido, impotence; testicular swelling; elevation or depression of blood sugar levels; syndrome of inappropriate ADH (antidiuretic hormone) secretion.

Other--Jaundice (simulating obstructive); altered liver function, hepatitis, and liver necrosis; weight gain or loss; perspiration; flushing; urinary frequency, nocturia; drowsiness, dizziness, weakness, fatigue; headache; parotid swelling; alopecia.

Withdrawal Symptoms--Though these are not indicative of addiction, abrupt cessation of treatment after prolonged therapy may produce nausea, headache, and malaise.

Read the entire FDA prescribing information for Nortriptyline Hydrochloride Oral Solution (Nortriptyline Hydrochloride Oral Solution)


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© Nortriptyline Hydrochloride Oral Solution Patient Information is supplied by Cerner Multum, Inc. and Nortriptyline Hydrochloride Oral Solution Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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