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Last reviewed on RxList: 5/13/2020
Novarel Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Novarel?

Novarel (chorionic gonadotropin for injection) is a polypeptide hormone used to treat Prepubertal cryptorchidism not due to anatomic obstruction. In general, HCG is thought to induce testicular descent in situations when descent would have occurred at puberty. HCG thus may help to predict whether or not orchiopexy will be needed in the future. Although, in some cases, descent following HCG administration is permanent, in most cases the response is temporary. Therapy is usually instituted between the ages of 4 and 9. Novareli is also used to treats elected cases of hypogonadotropic hypogonadism (hypogonadism secondary to a pituitary deficiency) in males, and for induction of ovulation and pregnancy in the anovulatory, infertile woman in whom the cause of anovulation is secondary and not due to primary ovarian failure, and who has been appropriately pretreated with human menotropins.

What Are Side Effects of Novarel?

Side effects of Novarel include:

  • headache,
  • irritability,
  • restlessness,
  • depression,
  • fatigue,
  • fluid retention (edema),
  • precocious puberty,
  • breast development in males (gynecomastia),
  • pain at the injection site, and
  • hypersensitivity reactions including redness, hives, rash, skin swelling, and shortness of breath

Dosage for Novarel

The dosage regimen of Novarel employed in any particular case will depend upon the indication for use, the age and weight of the patient, and the physician's preference.

Novarel In Children

Safety and effectiveness of Novarel in children below the age of 4 have not been established.

What Drugs, Substances, or Supplements Interact with Novarel?

Novarel may interact with other medicines.

Tell your doctor all medications and supplements you use.

Novarel During Pregnancy and Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Novarel; it may harm a fetus. It is unknown if Novarel is passes into breast milk. Because many drugs are excreted in human milk, caution should be exercised when HCG is administered to a breastfeeding woman.

Additional Information

Our Novarel (chorionic gonadotropin for injection) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Novarel Professional Information


(see WARNINGS) Headache, irritability, restlessness, depression, fatigue, edema, precocious puberty, gynecomastia, pain at the site of injection. Hypersensitivity reactions both localized and systemic in nature, including erythema, urticaria, rash, angioedema, dyspnea and shortness of breath, have been reported. The relationship of these allergic-like events to the polypeptide hormone or the diluent containing benzyl alcohol is not clear.

Read the entire FDA prescribing information for Novarel (Chorionic Gonadotropin for Injection)

Related Resources for Novarel

© Novarel Patient Information is supplied by Cerner Multum, Inc. and Novarel Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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