Medical Editor: John P. Cunha, DO, FACOEP
What Is Novolin N Innolet?
Novolin N InnoLet [NPH, Human Insulin Isophane Suspension (recombinant DNA origin)] is a form of insulin, a hormone produced in the body, used to treat diabetes. Novolin N InnoLet is available over-the-counter. Common side effects of Novolin N InnoLet include localized reactions such as red, swollen and itchy skin where the insulin has been injected.
What Are Side Effects of Novolin N Innolet?
The most common side effect of Novolin N InnoLet is low blood sugar (hypoglycemia). Symptoms of low blood sugar include:
- headache,
- nausea,
- hunger,
- confusion,
- drowsiness,
- weakness,
- dizziness,
- blurred vision,
- fast heartbeat,
- sweating,
- tremor,
- trouble concentrating,
- confusion, or
- seizure (convulsions)
Seek medical care or call 911 at once if you have the following serious side effects:
- Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
- Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
- Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.
This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.
Dosage for Novolin N Innolet
Novolin N is commonly known as NPH, Human Insulin Isophane Suspension (recombinant DNA origin). The concentration of this product is 100 units of insulin per milliliter.
What Drugs, Substances, or Supplements Interact with Novolin N Innolet?
Novolin N InnoLet may interact with albuterol, clonidine, reserpine, guanethidine, or beta-blockers. Tell your doctor all medications and supplements you use.
Novolin N Innolet During Pregnancy or Breastfeeding
Consult your doctor to discuss the best way to manage your diabetes while you are pregnant or breastfeeding.
Additional Information
Our Novolin N InnoLet [NPH, Human Insulin Isophane Suspension (recombinant DNA origin)] Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION
Diabetes is defined best as... See AnswerGet emergency medical help if you have signs of insulin allergy: redness or swelling where an injection was given, itchy skin rash over the entire body, trouble breathing, chest tightness, feeling like you might pass out, or swelling in your tongue or throat.
Call your doctor at once if you have:
- fluid retention--weight gain, swelling in your hands or feet, feeling short of breath; or
- low potassium--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.
Common side effects may include:
- low blood sugar;
- weight gain, swelling in your hands or feet;
- itching, mild skin rash; or
- thickening or hollowing of the skin where you injected the medicine.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW
Diabetes: What Raises and Lowers Your Blood Sugar Level? See SlideshowSIDE EFFECTS
A few people with diabetes develop red, swollen and itchy skin where the insulin has been injected. This is called a "local reaction" and it may occur if the injection is not properly made, if the skin is sensitive to the cleansing solution, or if you are allergic to the insulin being used. If you have a local reaction, tell your physician.
Generalized insulin allergy occurs rarely, but when it does it may cause a serious reaction, including skin rash over the body, shortness of breath, fast pulse, sweating, and a drop in blood pressure. If any of these symptoms develop, you should seek emergency medical care. If severe allergic reactions to insulin have occurred (i.e., generalized rash, swelling or breathing difficulties) you should be skin-tested with each new insulin preparation before it is used.
Read the entire FDA prescribing information for Novolin N Innolet (NPH, Human Insulin Isophane Suspension 3 ml Disposable Prefilled Syringe)
© Novolin N Innolet Patient Information is supplied by Cerner Multum, Inc. and Novolin N Innolet Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.
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