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NSAIDs (Nonsteroidal Antiinflammatory Drugs) (cont.)

Pharmacy Author:
Medical Editor:

With which drugs do NSAIDs interact?

NSAIDs may reduce the benefit of drugs used for treating hypertension because NSAIDs may increase blood pressure. NSAIDs decrease the elimination of lithium (Eskalith) and methotrexate (Rheumatrex) potentially leading to their toxicity, and reduce the action of diuretics ("water pills") by reducing blood flow to the kidneys. NSAIDs increase bleeding by decreasing the activity of blood platelets and therefore formation of blood clots. When used with other drugs that also increase bleeding, for example, warfarin (Coumadin), the likelihood of bleeding complications is increased. Prolonged use of NSAIDs with drugs that increase bleeding should be avoided.

What are some examples of approved NSAIDS in the United States?

The following list contains only NSAIDs that are commonly used:

Reviewed by:
Tova Alladice, M.D.
American Board of Physical Medicine & Rehabilitation

Medically Reviewed by a Doctor on 4/26/2016

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