Nubeqa vs. Xofigo

Reviewed on 11/30/2020

Are Nubeqa and Xofigo the Same Thing?

Nubeqa (darolutamide) and Xofigo (radium Ra 223 dichloride) are indicated for the treatment of patients with non-metastatic castration-resistant prostate cancer.

Xofigo is used in patients with non-metastatic castration-resistant prostate cancer and symptomatic bone metastases and no known visceral metastatic disease.

Nubeqa and Xofigo belong to different drug classes. Nubeqa is an androgen receptor inhibitor and Xofigo is a radiotherapeutic drug.

Side effects of Nubeqa that are different from Xofigo include fatigue, pain in extremities, and rash.

Side effects of Xofigo that are different from Nubeqa include nausea, diarrhea, vomiting, swelling of the legs and feet, and low red and white blood cell counts as well as low platelets.

Nubeqa may interact with rifampicin, itraconazole, midazolam, and rosuvastatin.

Xofigo may interact with other drugs.

What Are Possible Side Effects of Nubeqa?

Common side effects of Nubeqa include:

  • fatigue,
  • pain in extremities, and
  • rash

What Are Possible Side Effects of Xofigo?

Common side effects of Xofigo include:

  • nausea,
  • diarrhea,
  • vomiting,
  • swelling of the legs and feet, and
  • low red and white blood cell counts as well as low platelets

IMAGES

See Images

What Is Nubeqa?

Nubeqa (darolutamide) is an androgen receptor inhibitor indicated for the treatment of patients with non-metastatic castration-resistant prostate cancer.

What Is Xofigo?

Xofigo (radium Ra 223 dichloride) is a radiotherapeutic drug used to treat patients with castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastatic disease.

What Drugs Interact With Nubeqa?

Nubeqa may interact with rifampicin, itraconazole, midazolam, and rosuvastatin. Tell your doctor all medications and supplements you use.

What Drugs Interact With Xofigo?

Xofigo may interact with other drugs. Tell your doctor all medications and supplements you use.

How Should Nubeqa be Taken?

The dose of Nubeqa is 600 mg, (two 300 mg tablets) administered orally twice daily with food. Patients should also receive a gonadotropin-releasing hormone (GnRH) analog concurrently or should have had bilateral orchiectomy.

How Should Xofigo be Taken?

The dose regimen of Xofigo is 50 kBq (1.35 microcurie) per kg body weight, given at 4 week intervals for 6 injections.

SLIDESHOW

Screening Tests Every Man Should Have See Slideshow
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
Bayer Pharmaceuticals. Nubeqa Product Information

https://www.nubeqahcp.com/

Bayer Pharmaceuticals. Xofigo Product Information.

https://www.xofigo-us.com/

Health Solutions From Our Sponsors