Nurtec ODT vs. Relpax

Reviewed on 12/15/2020

Are Nurtec ODT and Relpax the Same Thing?

Nurtec ODT (rimegepant) and Relpax (eletriptan hydrobromide) are used to treat migraine headaches.

Nurtec ODT and Relpax belong to different drug classes. Nurtec ODT is a calcitonin gene-related peptide receptor antagonist and Relpax is a selective serotonin receptor agonist.

Side effects of Nurtec ODT and Relpax that are similar include nausea.

Side effects of Nurtec ODT that are different from Relpax include hypersensitivity reactions (including shortness of breath and severe rash).

Side effects of Relpax that are different from Nurtec ODT include mild headache (not a migraine), tingling/numbness, upset stomach, stomach pain or cramps, weakness, drowsiness, dizziness, pressure or heavy feeling in any part of your body, dry mouth, and flushing (warmth, redness, or tingling under your skin).

Nurtec ODT may interact with strong and moderate CYP3A4 inhibitors, strong and moderate CYP3A inducers, and inhibitors of P-gp or BCRP.

Relpax may interact with nefazodone, azole antifungals, antibiotics, protease inhibitors, ergot-type drugs or other migraine drugs, antidepressants, St. John's wort, antihistamines, anti-seizure drugs, medicines for sleep or anxiety, muscle relaxants, narcotic pain relievers, and psychiatric medicines.

What Are Possible Side Effects of Nurtec ODT?

Common side effects of Nurtec ODT include:

  • nausea and
  • hypersensitivity (including shortness of breath and severe rash)

What Are Possible Side Effects of Relpax?

Common side effects of Relpax include:

  • mild headache (not a migraine),
  • tingling/numbness,
  • nausea,
  • upset stomach,
  • stomach pain or cramps,
  • weakness,
  • drowsiness,
  • dizziness,
  • pressure or heavy feeling in any part of your body,
  • dry mouth, or
  • flushing (warmth, redness, or tingling under your skin).

Tell your doctor if you have serious side effects of Relpax including:

  • blue fingers/toes/nails, or
  • cold hands or feet.

SLIDESHOW

16 Surprising Headache Triggers and Tips for Pain Relief See Slideshow

What Is Nurtec ODT?

Nurtec ODT (rimegepant) is a calcitonin gene-related peptide receptor antagonist used for acute treatment of migraine with or without aura in adults.

What Is Relpax?

Relpax (eletriptan hydrobromide) is a selective serotonin receptor agonist used to treat migraine headaches. Relpax will only treat a headache that has already begun. Relpax will not prevent headaches or reduce the number of attacks.

What Drugs Interact With Nurtec ODT?

Nurtec ODT may interact with other medicines such as:

  • strong CYP3A4 inhibitors,
  • moderate CYP3A4 inhibitors,
  • strong and moderate CYP3A inducers, and
  • inhibitors of P-gp or BCRP.

Tell your doctor all medications and supplements you use.

What Drugs Interact With Relpax?

Relpax should not be used with sibutramine because a very serious interaction may occur. Relpax should not be used within 72 hours of use of drugs affecting liver enzymes that remove eletriptan from your body such as nefazodone, azole antifungals, antibiotics, and protease inhibitors. Relpax should not be used within 24 hours of use of ergot-type drugs or other migraine drugs because of serious interactions. Antidepressants, St. John's wort, antihistamines, anti-seizure drugs, medicine for sleep or anxiety, muscle relaxants, narcotic pain relievers, and psychiatric medicines may all adversely interact with this drug. Discuss all medications you are taking with your doctor.

How Should Nurtec ODT be Taken?

The recommended dose of Nurtec ODT is 75 mg taken orally, as needed.

How Should Relpax be Taken?

A single dose of 20 mg or 40 mg is effective for the acute treatment of migraine in adults. After taking Relpax, you must wait 2 hours before taking another dose.

QUESTION

Who suffers more frequently from migraine headaches? See Answer
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References
Biohaven Pharmaceuticals. Nurtec ODT Product Information

https://www.nurtec.com/

Dailymed. Relpax Product Information.

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=85745375-fcb6-4edc-b6db-a77b4a5f3e8c&audience=consumer

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