Nurtec ODT vs. Reyvow

Reviewed on 12/15/2020

Are Nurtec ODT and Reyvow the Same Thing?

Nurtec ODT (rimegepant) and Reyvow (lasmiditan) are used for acute treatment of migraine with or without aura in adults.

Nurtec ODT and Reyvow belong to different drug classes. Nurtec ODT is a calcitonin gene-related peptide receptor antagonist and Reyvow is a serotonin (5-HT) 1F receptor agonist.

Side effects of Nurtec ODT and Reyvow that are similar include nausea.

Side effects of Nurtec ODT that are different from Reyvow include hypersensitivity reactions (including shortness of breath and severe rash).

Side effects of Reyvow that are different from Nurtec ODT include dizziness, fatigue, numbness and tingling, sedation, and vomiting.

Both Nurtec ODT and Reyvow may interact with P-gp or BCRP substrates.

Nurtec ODT may also interact with strong and moderate CYP3A4 inhibitors and strong and moderate CYP3A inducers.

Reyvow may also interact with alcohol or other CNS depressants, antidepressants, MAO inhibitors, trazodone, dextromethorphan, St. John's wort, and medications that lower heart rate.

What Are Possible Side Effects of Nurtec ODT?

Common side effects of Nurtec ODT include:

  • nausea and
  • hypersensitivity (including shortness of breath and severe rash)

What Are Possible Side Effects of Reyvow?

Common side effects of Reyvow include:

  • dizziness,
  • fatigue,
  • numbness and tingling,
  • sedation,
  • nausea, and
  • vomiting

SLIDESHOW

16 Surprising Headache Triggers and Tips for Pain Relief See Slideshow

What Is Nurtec ODT?

Nurtec ODT (rimegepant) is a calcitonin gene-related peptide receptor antagonist used for acute treatment of migraine with or without aura in adults.

What Is Reyvow?

Reyvow (lasmiditan) is a serotonin (5-HT) 1F receptor agonist indicated for the acute treatment of migraine with or without aura in adults. Reyvow is not indicated for the preventive treatment of migraine.

What Drugs Interact With Nurtec ODT?

Nurtec ODT may interact with other medicines such as:

  • strong CYP3A4 inhibitors,
  • moderate CYP3A4 inhibitors,
  • strong and moderate CYP3A inducers, and
  • inhibitors of P-gp or BCRP.

Tell your doctor all medications and supplements you use.

What Drugs Interact With Reyvow?

Reyvow may interact with:

  • alcohol or other CNS depressants,
  • antidepressants,
  • MAO inhibitors,
  • trazodone,
  • dextromethorphan,
  • St. John’s wort,
  • medications that lower heart rate, and
  • P-gp or BCRP substrates

How Should Nurtec ODT be Taken?

The recommended dose of Nurtec ODT is 75 mg taken orally, as needed.

How Should Reyvow be Taken?

The recommended dose of Reyvow is 50 mg, 100 mg, or 200 mg taken orally, as needed. No more than one dose of Reyvow should be taken in 24 hours.

QUESTION

Who suffers more frequently from migraine headaches? See Answer
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References
Biohaven Pharmaceuticals. Nurtec ODT Product Information

https://www.nurtec.com/

Lilly. Reyvow Drug Information.

https://investor.lilly.com/news-releases/news-release-details/lillys-reyvowtm-lasmiditan-first-and-only-medicine-new-class

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