Last updated on RxList: 7/23/2020
Nutrilipid Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

What Is Nutrilipid?

Nutrilipid (lipid injectable emulsion) is indicated as a source of calories and essential fatty acids for parenteral nutrition and as a source of essential fatty acids when a deficiency occurs when oral or enteral nutrition is not possible, insufficient, or contraindicated.

What Are Side Effects of Nutrilipid?

Common side effects of Nutrilipid include high lipid (fat) levels in the blood (hyperlipidemia), increased tendency toward blood clots (hypercoagulability), blood clots in the veins (thrombophlebitis), low levels of platelets in the blood (thrombocytopenia), and yellowing of the skin or eyes (jaundice).

Dosage for Nutrilipid

The dose of Nutrilipid is based on the patient's age and body weight.

What Drugs, Substances, or Supplements Interact with Nutrilipid?

Nutrilipid may interact with anticoagulants. Tell your doctor all medications and supplements you use.

Nutrilipid During Pregnancy and Breastfeeding

During pregnancy, Nutrilipid should be administered only if needed. It is unknown how it might affect a fetus. It is unknown if Nutrilipid passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Nutrilipid (lipid injectable emulsion) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Adverse Reactions described elsewhere in labeling:

  • Death in Preterm Infants [see WARNINGS AND PRECAUTIONS]
  • Hypersensitivity Reactions [see WARNINGS AND PRECAUTIONS]
  • Fat Overload Syndrome [see WARNINGS AND PRECAUTIONS]
  • Refeeding Syndrome [see WARNINGS AND PRECAUTIONS]
  • Aluminum Toxicity [see WARNINGS AND PRECAUTIONS]
  • Risk of Parenteral Nutrition Associated Liver Disease [see WARNINGS AND PRECAUTIONS]
  • Hypertriglyceridemia [see WARNINGS AND PRECAUTIONS]

Clinical Trials Experience

Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice.

Adverse reactions reported with other intravenous lipid emulsions include hyperlipidemia, hypercoagulability, thrombophlebitis, and thrombocytopenia.

Adverse reactions reported in long-term use with other intravenous lipid emulsions include hepatomegaly, jaundice due to central lobular cholestasis, splenomegaly, thrombocytopenia, leukopenia, abnormalities in liver function tests, brown pigmentation of the liver and overloading syndrome (focal seizures, fever, leukocytosis, hepatomegaly, splenomegaly and shock).

Read the entire FDA prescribing information for Nutrilipid (20% Soybean oil I.V. Fat Emulsion)


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© Nutrilipid Patient Information is supplied by Cerner Multum, Inc. and Nutrilipid Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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