Ocrevus vs. Extavia

Reviewed on 11/25/2019

Are Ocrevus and Extavia the Same Thing?

Ocrevus (ocrelizumab) injection and Extavia (interferon beta-1b) Kit are used to treat relapsing forms of multiple sclerosis (MS).

Ocrevus is also used to treat primary progressive forms of multiple sclerosis (MS).

Ocrevus Extavia belong to different drug classes. Ocrevus is a CD20-directed cytolytic antibody and Extavia is made from human proteins.

Side effects of Ocrevus that are different from Extavia include upper and lower respiratory tract infections, infusion reactions (itching, rash, hives, redness, bronchospasm, swollen and sore throat, mouth pain, shortness of breath, flushing, hypotension, fever, fatigue, headache, dizziness, nausea, and fast heart rate), skin infections, depression, back pain, and pain in the extremities.

Side effects of Extavia that are different from Ocrevus include headache, muscle pain or weakness, sleep problems (insomnia), stomach or abdominal pain, swelling in your hands or feet, skin rash, hives, itching, irregular menstrual periods, flu-like symptoms (chills, fever, feeling unwell), increased sweating, decreased white blood cell count, injection site reactions (bruising, swelling, redness, pain, warm feeling, or leaking of fluid), stuffy nose, and irregular heartbeats.

Ocrevus may interact with other immune-modulating or immunosuppressive therapies, including immunosuppressant doses of corticosteroids.

Extavia may interact with alcohol and other drugs.

What Are Possible Side Effects of Ocrevus?

Common side effects of Ocrevus include:

  • upper respiratory tract infections,
  • infusion reactions (itching, rash, hives, redness, bronchospasm, swollen and sore throat, mouth pain, shortness of breath, flushing, hypotension, fever, fatigue, headache, dizziness, nausea, and fast heart rate),
  • skin infections,
  • lower respiratory tract infections,
  • depression,
  • back pain, and
  • pain in the extremities.

What Are Possible Side Effects of Extavia?

Common side effects of Extavia include:

  • headache,
  • muscle pain or weakness,
  • sleep problems (insomnia),
  • stomach or abdominal pain,
  • swelling in your hands or feet,
  • skin rash,
  • hives,
  • itching,
  • irregular menstrual periods,
  • flu-like symptoms (chills, fever, general feeling of being unwell),
  • increased sweating,
  • decreased white blood cell count,
  • injection site reactions (bruising, swelling, redness, pain, warm feeling, or leaking of fluid),
  • stuffy nose, or
  • irregular heartbeat

What Is Ocrevus?

Ocrevus (ocrelizumab) injection is aCD20-directed cytolytic antibody indicated for the treatment of patients with relapsing or primary progressive forms of multiple sclerosis.

What Is Extavia?

Extavia (interferon beta-1b) Kit is made from human proteins and is used to treat relapsing multiple sclerosis (MS). Extavia will not cure MS, it will only decrease the frequency of relapse symptoms.

SLIDESHOW

What Is Multiple Sclerosis? MS Symptoms, Causes, Diagnosis See Slideshow

What Drugs Interact With Ocrevus?

Ocrevus may interact with other immune-modulating or immunosuppressive therapies, including immunosuppressant doses of corticosteroids. Tell your doctor all medications and supplements you use.

What Drugs Interact With Extavia?

Tell your doctor all medications and supplements you use. Do not use Extavia if you are pregnant. It may be harmful to a fetus, or may cause a miscarriage. Tell your doctor if you become pregnant during treatment. It is unknown if this drug passes into breast milk or if it could harm a nursing baby. Consult your doctor before breastfeeding.

How Should Ocrevus Be Taken?

Hepatitis B virus screening is required before the first dose of Ocrevus. Pre-medicate with methylprednisolone (or an equivalent corticosteroid) and an antihistamine prior to each infusion. The starting dose of Ocrevus is 300 mg intravenous infusion, followed two weeks later by a second 300 mg intravenous infusion. Subsequent doses of Ocrevus are 600 mg intravenous infusion every 6 months.

How Should Extavia Be Taken?

The recommended dose of Extavia is 0.25 mg injected subcutaneously every other day. Extavia may interact with other drugs.

QUESTION

What kind of disease is multiple sclerosis? See Answer
Disclaimer

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

References
Genentech. Ocrevus Product Monograph.

https://www.ocrevus.com

Novartis. Extavia Product Information.

https://www.extavia.com

Health Solutions From Our Sponsors