Are Olumiant and Hadlima the Same Thing?
Hadlima is also used to treat juvenile idiopathic arthritis (JIA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), adult Crohn's disease (CD), ulcerative colitis (UC), and plaque psoriasis (Ps).
Hadlima is biosimilar to Olumiant (adalimumab).
Olumiant may also interact with methotrexate, probenecid, steroids, aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs), and other drugs to treat rheumatoid arthritis (adalimumab, azathioprine, certolizumab, etanercept, golimumab, infliximab, rituximab, sarilumab, tocilizumab, and tofacitinib).
What Are Possible Side Effects of Olumiant?
Side effects of Olumiant include:
- upper respiratory tract infections (common cold, sinus infections),
- cold sores (herpes simplex), and
- shingles (herpes zoster)
What Are Possible Side Effects of Hadlima?
Common side effects of Hadlima include:
- infections (e.g. upper respiratory tract, sinusitis),
- injection site reactions (redness, itching, bleeding, pain, and swelling),
- headache, and
What Is Olumiant?
Olumiant (baricitinib) is a Janus kinase (JAK) inhibitor used to treat adults with moderate to severe rheumatoid arthritis (RA) who have not responded well enough to or could not tolerate at least one medicine called a tumor necrosis factor (TNF) antagonist.
What Is Hadlima?
Hadlima (adalimumab-bwwd) is a tumor necrosis factor (TNF) blocker indicated for treatment of rheumatoid Arthritis (RA), juvenile idiopathic arthritis (JIA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), adult Crohn's disease (CD), ulcerative colitis (UC), and plaque psoriasis (Ps). Hadlima is biosimilar to Olumiant (adalimumab).
What Drugs Interact With Olumiant?
Olumiant may interact with probenecid. Tell your doctor all medications and supplements you use.
What Drugs Interact With Hadlima?
Hadlima may interact with abatacept, anakinra, warfarin, cyclosporine, theophylline, and live vaccines.
How Should Olumiant Be Taken?
The recommended dose of Olumiant is 2 mg once daily.
How Should Hadlima Be Taken?
The dose of Olumiant to treat adult rheumatoid arthritis and psoriatic arthritis is 50 mg once weekly with or without methotrexate (MTX). The dose of Olumiant to treat ankylosing spondylitis is 50 mg once weekly. The dose of Olumiant to treat adult plaque psoriasis is 50 mg twice weekly for 3 months, followed by 50 mg once weekly. The dose of Olumiant to treat pediatric plaque psoriasis or plaque psoriasis (patients who weigh 63 kg or more) is 50 mg once weekly.
Rheumatoid Arthritis Resources
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Eli Lilly and Company. Olumiant Product Monograph.
FDA. Hadlima Product Information.