Opium Tincture

Reviewed on 7/5/2022

What Is Opium Tincture and How Does It Work?

Opium Tincture is a prescription medication used for treating the symptoms of diarrhea. 

  • Opium Tincture is available under the following different brand names: 

What Are Dosages of Opium Tincture?

Adult dosage

Oral liquid: Schedule II

  • 118 mL/bottle
  • Each mL contains 10 mg of anhydrous morphine


Adult dosage

  • 6 mg (0.6 mL) orally every 6hours; not to exceed 6 mL/day

Dosage Considerations – Should be Given as Follows: 

  • See “Dosages”

What Are Side Effects Associated with Using Opium Tincture?

Common side effects of Opium Tincture include:

  • light-headedness,
  • dizziness,
  • drowsiness,
  • tiredness,
  • restlessness,
  • nausea,
  • vomiting,
  • upset stomach,
  • loss of appetite,
  • constipation,
  • increased sweating, or
  • flushing (warmth, redness, or tingly feeling under the skin).

Serious side effects of Opium Tincture include:

  • severe constipation, bloating, stomach cramps;
  • urinating less than usual or not at all;
  • fast, pounding, or uneven heartbeats;
  • light-headed feeling;
  • severe drowsiness
  • weak or shallow breathing; or
  • seizures (convulsions).

Rare side effects of Opium Tincture include:

  • none 

This is not a complete list of side effects and other serious side effects or health problems that may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

What Other Drugs Interact with Opium Tincture?

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first.

  • Opium Tincture has severe interactions with the following drugs:
  • Opium Tincture has serious interactions with at least 26 other drugs.
  • Opium Tincture has moderate interactions with at least 184 other drugs.
  • Opium Tincture has severe interactions with the following drugs:

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all the products you use. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions or concerns.

What Are Warnings and Precautions for Opium Tincture?


Effects of drug abuse

  • None

Short-Term Effects

  • See “What Are Side Effects Associated with Using Opium Tincture?”

Long-Term Effects

  • See “What Are Side Effects Associated with Using Opium Tincture?”


  • Caution in asthma, severe prostatic hypertrophy, thyroid dysfunction, hepatic disease, history of opioid dependence, patients morbidly obese, and concurrent CNS depressants
  • Caution in patients with head trauma
  • Opium Tincture contains 25 times more morphine than paregoric & should never be confused with the latter
  • Caution in patients with acute adrenal insufficiency (e.g., Addison's disease)
  • Caution in patients with biliary tract dysfunction
  • Caution in patients with GI hemorrhage

Pregnancy and Lactation

  • Unknown whether the drug may cause fetal harm when administered to pregnant females or can affect reproduction capacity
  • No animal studies conducted
  • Lactation
    • Exercise caution when administering to nursing females

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