Are Orencia and Hadlima the Same Thing?
Hadlima is also used to treat juvenile idiopathic arthritis (JIA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), adult Crohn's disease (CD), ulcerative colitis (UC), and plaque psoriasis (Ps).
Hadlima is biosimilar to Humira (adalimumab).
Side effects of Orencia that are different from Hadlima include nausea, diarrhea, stomach pain, indigestion, dizziness, flushing, back pain, and cold symptoms such as stuffy head/nose, sneezing, sore throat, or cough.
Side effects of Orencia and Hadlima that are similar include headache.
Side effects of Hadlima that are different from Orencia include infections (e.g. upper respiratory tract, sinusitis), injection site reactions (redness, itching, bleeding, pain, and swelling), and rash.
Both Orencia around Hadlima may interact with anakinra and live vaccines.
What Are Possible Side Effects of Orencia?
Side effects of Orencia include:
- stomach pain,
- back pain, or
- cold symptoms such as stuffy head/nose, sneezing, sore throat, or cough.
Serious side effects of Orencia include:
- night sweats,
- flu symptoms,
- weight loss,
- feeling very tired,
- fatal infections,
- shortness of breath,
- changes in the amount of urine,
- pain when urinating, and
- severe abdominal pain.
What Are Possible Side Effects of Hadlima?
Common side effects of Hadlima include:
- infections (e.g. upper respiratory tract, sinusitis),
- injection site reactions (redness, itching, bleeding, pain, and swelling),
- headache, and
What Is Orencia?
Orencia (abatacept) is a recombinant DNA generated fusion protein used to treat the symptoms of rheumatoid arthritis and to prevent joint damage caused by these conditions. Orencia is also used to treat arthritis in children who are at least 6 years old. Orencia is not a cure for any autoimmune disorder and only treats symptoms.
What Is Hadlima?
Hadlima (adalimumab-bwwd) is a tumor necrosis factor (TNF) blocker indicated for treatment of rheumatoid Arthritis (RA), juvenile idiopathic arthritis (JIA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), adult Crohn's disease (CD), ulcerative colitis (UC), and plaque psoriasis (Ps). Hadlima is biosimilar to Orencia (adalimumab).
What Drugs Interact With Orencia?
There may be other drugs that can interact with Orencia. The prescribing doctor needs to know all medications (including herbals) that the person is taking. During pregnancy, Orencia should be used only when prescribed. It is unknown if Orencia passes into breast milk or if it would harm a nursing baby. Breastfeeding is not recommended while using this drug.
What Drugs Interact With Hadlima?
Hadlima may interact with abatacept, anakinra, warfarin, cyclosporine, theophylline, and live vaccines.
How Should Orencia Be Taken?
Orencia is supplied in single use vials at a strength of 250mg per vial. Orencia is administered intravenously (IV) as a 30-minute infusion. Dosing is based on the patient's weight. Following the initial intravenous administration, an IV infusion is given at 2 and 4 weeks after the first infusion and every 4 weeks thereafter.
How Should Hadlima Be Taken?
The dose of Orencia to treat adult rheumatoid arthritis and psoriatic arthritis is 50 mg once weekly with or without methotrexate (MTX). The dose of Orencia to treat ankylosing spondylitis is 50 mg once weekly. The dose of Orencia to treat adult plaque psoriasis is 50 mg twice weekly for 3 months, followed by 50 mg once weekly. The dose of Orencia to treat pediatric plaque psoriasis or plaque psoriasis (patients who weigh 63 kg or more) is 50 mg once weekly.
Rheumatoid Arthritis Resources
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Bristol-Myers Squibb Company. Orencia Product Information.
FDA. Hadlima Product Information.