Orudis vs. Celebrex

Are Orudis and Celebrex the Same Thing?

Orudis (ketoprofen) and Celebrex (celecoxib) are nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat pain or inflammation caused by arthritis. Orudis and Celebrex are also used to treat menstrual pain and cramps.

Celebrex is also used to treat familial adenomatous polyposis (FAP) and acute pain.

The brand name Orudis is no longer available in the U.S. It is available in its generic form, ketoprofen.

Side effects of Orudis and Celebrex that are similar include upset stomach, indigestion/heartburn, stomach/abdominal pain, diarrhea, bloating, gas, dizziness, nervousness, headache, skin rash, and runny nose.

Side effects of Orudis that are different from Celebrex include unusual tiredness, constipation, lightheadedness, drowsiness, loss of appetite, itching, dry mouth, increased sweating, blurred vision, and ringing in your ears.

Side effects of Celebrex that are different from Orudis include nausea, stuffy nose, sore throat, insomnia, and serious stomach and intestinal ulcers.

Both Orudis and Celebrex may interact with other nonsteroidal anti-inflammatory drugs (NSAIDs), blood thinners, and lithium.

Orudis may also interact with cyclosporine, methotrexate, probenecid, steroids, and aspirin.

Celebrex may also interact with other cold/allergy/pain medicine that contains NSAIDs, antidepressants, diuretics (water pills), fluconazole, heart or blood pressure medications, and ACE inhibitors.

What Are Possible Side Effects of Orudis?

Side effects of Orudis include:

  • upset stomach,
  • heartburn,
  • stomach pain,
  • unusual tiredness,
  • constipation,
  • diarrhea,
  • bloating,
  • gas,
  • dizziness,
  • nervousness,
  • lightheadedness,
  • drowsiness,
  • loss of appetite,
  • headache,
  • skin itching or rash,
  • dry mouth,
  • increased sweating,
  • runny nose,
  • blurred vision, or
  • ringing in your ears.

Tell your doctor if you have serious side effects of Orudis (ketoprofen) including:

What Are Possible Side Effects of Celebrex?

Common side effects of Celebrex include:

  • headache,
  • abdominal pain,
  • indigestion,
  • diarrhea,
  • nausea,
  • upset stomach,
  • bloating,
  • gas,
  • dizziness,
  • nervousness,
  • headache,
  • runny or stuffy nose,
  • sore throat,
  • skin rash, and
  • insomnia.

Celebrex may cause serious stomach and intestinal ulcers.


What Is Rheumatoid Arthritis (RA)? Symptoms, Treatment, Diagnosis See Slideshow

What Is Orudis?

Orudis (ketoprofen) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain or inflammation caused by arthritis. Orudis is also used to treat menstrual pain. The brand name Orudis is no longer available in the U.S. It is available in its generic form, ketoprofen.

What Is Celebrex?

Celebrex used to treat pain and redness, swelling, and heat (inflammation) from medical conditions such as different types of arthritis, menstrual cramps, and other types of short-term pain.

What Drugs Interact With Orudis?

Ketoprofen may interact with cyclosporine, lithium, methotrexate, probenecid, blood thinners, steroids, aspirin, or other nonsterioidal anti-inflammatory drugs (NSAIDs). Tell your doctor all medications and supplements you use. During the first 6 months of pregnancy, ketoprofen should be used only when prescribed. Ketoprofen is not recommended for use during the last 3 months of pregnancy due to possible harm to the fetus and interference with normal labor/delivery. It is unknown if ketoprofen passes into breast milk or if it will harm a nursing infant. Consult your doctor before breastfeeding.

What Drugs Interact With Celebrex?

Do not take Celebrex:

  • if you have had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAIDs.
  • right before or after heart bypass surgery.


The term arthritis refers to stiffness in the joints. See Answer

How Should Orudis Be Taken?

The dosage of Orudis is one tablet twice daily, 375 mg anaprox/20 mg esomeprazole or 500 mg anaprox/20 mg esomeprazole.

How Should Celebrex Be Taken?

The usual starting dose of Orudis (ketoprofen) is 50 or 75 mg of immediate release capsules every 6 to 8 hours, or 200 mg of extended release capsules once daily. The maximum dose of ketoprofen is 300 mg daily of immediate release capsules or 200 mg daily of extended release capsules. Ketoprofen should be taken with food in order to avoid stomach upset.

All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).

Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.

Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.

If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.

You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.

FDA. Orudis Product Information


Pfizer. Celebrex Product Information.


Health Solutions From Our Sponsors