Orudis vs. Celebrex

Orudis (ketoprofen) and Celebrex (celecoxib) are nonsteroidal anti-inflammatory drugs (NSAIDs) used to treat pain or inflammation caused by arthritis. Orudis and Celebrex are also used to treat menstrual pain and cramps.

Celebrex is also used to treat familial adenomatous polyposis (FAP) and acute pain.

The brand name Orudis is no longer available in the U.S. It is available in its generic form, ketoprofen.

Side effects of Orudis and Celebrex that are similar include upset stomach, indigestion/heartburn, stomach/abdominal pain, diarrhea, bloating, gas, dizziness, nervousness, headache, skin rash, and runny nose.

Side effects of Orudis that are different from Celebrex include unusual tiredness, constipation, lightheadedness, drowsiness, loss of appetite, itching, dry mouth, increased sweating, blurred vision, and ringing in your ears.

Side effects of Celebrex that are different from Orudis include nausea, stuffy nose, sore throat, insomnia, and serious stomach and intestinal ulcers.

Both Orudis and Celebrex may interact with other nonsteroidal anti-inflammatory drugs (NSAIDs), blood thinners, and lithium.

Orudis may also interact with cyclosporine, methotrexate, probenecid, steroids, and aspirin.

Celebrex may also interact with other cold/allergy/pain medicine that contains NSAIDs, antidepressants, diuretics (water pills), fluconazole, heart or blood pressure medications, and ACE inhibitors.

Side effects of Orudis include:

• upset stomach,
• heartburn,
• stomach pain,
• unusual tiredness,
• constipation,
• diarrhea,
• bloating,
• gas,
• dizziness,
• nervousness,
• lightheadedness,
• drowsiness,
• loss of appetite,
• headache,
• skin itching or rash,
• dry mouth,
• increased sweating,
• runny nose,
• blurred vision, or
• ringing in your ears.

Tell your doctor if you have serious side effects of Orudis (ketoprofen) including:

• allergic reaction (hives, difficulty breathing, or swelling of your face, lips, tongue, or throat),
• chest pain,
• bloody or tarry stools,
• urinating less than usual or not at all,
• confusion,
• depression,
• fever, or
• fast or irregular heartbeat.

Common side effects of Celebrex include:

• headache,
• abdominal pain,
• indigestion,
• diarrhea,
• nausea,
• upset stomach,
• bloating,
• gas,
• dizziness,
• nervousness,
• headache,
• runny or stuffy nose,
• sore throat,
• skin rash, and
• insomnia.

Celebrex may cause serious stomach and intestinal ulcers.

Orudis (ketoprofen) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain or inflammation caused by arthritis. Orudis is also used to treat menstrual pain. The brand name Orudis is no longer available in the U.S. It is available in its generic form, ketoprofen.

Celebrex used to treat pain and redness, swelling, and heat (inflammation) from medical conditions such as different types of arthritis, menstrual cramps, and other types of short-term pain.

Ketoprofen may interact with cyclosporine, lithium, methotrexate, probenecid, blood thinners, steroids, aspirin, or other nonsterioidal anti-inflammatory drugs (NSAIDs). Tell your doctor all medications and supplements you use. During the first 6 months of pregnancy, ketoprofen should be used only when prescribed. Ketoprofen is not recommended for use during the last 3 months of pregnancy due to possible harm to the fetus and interference with normal labor/delivery. It is unknown if ketoprofen passes into breast milk or if it will harm a nursing infant. Consult your doctor before breastfeeding.

Do not take Celebrex:

• if you have had an asthma attack, hives, or other allergic reaction with aspirin or any other NSAIDs.
• right before or after heart bypass surgery.

The dosage of Orudis is one tablet twice daily, 375 mg anaprox/20 mg esomeprazole or 500 mg anaprox/20 mg esomeprazole.

The usual starting dose of Orudis (ketoprofen) is 50 or 75 mg of immediate release capsules every 6 to 8 hours, or 200 mg of extended release capsules once daily. The maximum dose of ketoprofen is 300 mg daily of immediate release capsules or 200 mg daily of extended release capsules. Ketoprofen should be taken with food in order to avoid stomach upset.