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Oxbryta

Last reviewed on RxList: 10/13/2020
Oxbryta Patient Information Including Side Effects

Brand Names: Oxbryta

Generic Name: voxelotor

What is voxelotor (Oxbryta)?

Voxelotor is used to treat sickle cell disease in adults and children at least 12 years old.

Voxelotor is sometimes given together with another medicine called hydroxyurea.

Voxelotor was approved by the US Food and Drug Administration (FDA) on an "accelerated" basis. In clinical studies, some people responded to this medicine, but further studies are needed.

Voxelotor may also be used for purposes not listed in this medication guide.

What are the possible side effects of voxelotor (Oxbryta)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Common side effects may include:

  • headache;
  • stomach pain, nausea, diarrhea;
  • tiredness;
  • rash; or
  • fever.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about voxelotor (Oxbryta)?

Follow all directions on your medicine label and package. Tell each of your healthcare providers about all your medical conditions, allergies, and all medicines you use.

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Oxbryta Patient Information including How Should I Take

What should I discuss with my healthcare provider before taking voxelotor (Oxbryta)?

You should not use voxelotor if you are allergic to it.

Tell your doctor if you have ever had:

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Do not breastfeed while using this medicine, and for at least 2 weeks after your last dose.

Voxelotor is not approved for use by anyone younger than 12 years old.

How should I take voxelotor (Oxbryta)?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

You may take voxelotor with or without food.

Swallow the tablet whole and do not crush, chew, or break it.

If you are receiving exchange transfusions, voxelotor can affect the results of certain blood tests. Tell any doctor who treats you that you are using voxelotor.

You should not stop using voxelotor without your doctor's advice.

Store at room temperature away from moisture and heat. Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative.

QUESTION

Sickle cell disease is named after a farming tool. See Answer
Oxbryta Patient Information including If I Miss a Dose

What happens if I miss a dose (Oxbryta)?

Skip the missed dose and use your next dose at the regular time. Do not use two doses at one time.

What happens if I overdose (Oxbryta)?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking voxelotor (Oxbryta)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect voxelotor (Oxbryta)?

Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.

Many drugs can affect voxelotor. This includes prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information (Oxbryta)?

Your pharmacist can provide more information about voxelotor.


Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

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