Last updated on RxList: 5/5/2016
Oxsoralen Side Effects Center

Last reviewed on RxList 5/05/2016

Oxsoralen (methoxsalen lotion) is a topical repigmenting agent used in vitiligo in conjunction with controlled doses of ultraviolet A (320-400 nm) or sunlight. Common side effects of Oxsoralen include:

  • minor blistering, and
  • severe burns of the treated area from overexposure to UVA, including sunlight
The dose of Oxsoralen Lotion is applied to a well-defined area of vitiligo by the physician and the area is then exposed to a suitable source of UVA. Oxsoralen may interact with other drugs. Tell your doctor all medications and supplements you use. During pregnancy, Oxsoralen should only be used if prescribed. It is unknown if it would affect a fetus. It is unknown if Oxsoralen passes into breast milk. Consult your doctor before breastfeeding.

Our Oxsoralen (methoxsalen lotion) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Oxsoralen Professional Information


Systemic adverse reactions have not been reported. The most common adverse reaction is severe burns of the treated area from overexposure to UVA, including sunlight. TREATMENT MUST BE INDIVIDUALIZED. Minor blistering of the skin is not a contraindication to further treatment and generally heals without incident. Treatment would be the standard for burn therapy. Since 1953, many studies have demonstrated the safety and effectiveness of topical methoxsalen and UVA for the treatment of vitiligo when used as directed. (Lerner, A.B., et al, 1953)6 (Fitzpatrick, T.B., et al, 1966)7 (Fulton, James F. et al, 1969)8

Read the entire FDA prescribing information for Oxsoralen (Methoxsalen Lotion)


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© Oxsoralen Patient Information is supplied by Cerner Multum, Inc. and Oxsoralen Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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