Pancreatic Cancer (cont.)
Francis W. Nugent, MD
Dr. F.W. Nugent is a medical oncologist specializing in gastrointestinal cancers with a special interest in pancreatic cancer. Dr. Nugent graduated from Middlebury College with a bachelors degree in religion before graduating from Albany Medical College. He presently serves as vice-chairman of medical oncology at the Lahey Clinic in Burlington, Massachusetts.
Keith E. Stuart, MD
Dr. Keith E. Stuart is a medical oncologist specializing in the study and treatment of cancers involving the gastrointestinal tract, with a special interest in tumors involving the liver. He was educated at Harvard University (graduating magna cum laude) and Albert Einstein College of Medicine and did his medical training at the New England Deaconess Hospital.
Charles Patrick Davis, MD, PhD
Dr. Charles "Pat" Davis, MD, PhD, is a board certified Emergency Medicine doctor who currently practices as a consultant and staff member for hospitals. He has a PhD in Microbiology (UT at Austin), and the MD (Univ. Texas Medical Branch, Galveston). He is a Clinical Professor (retired) in the Division of Emergency Medicine, UT Health Science Center at San Antonio, and has been the Chief of Emergency Medicine at UT Medical Branch and at UTHSCSA with over 250 publications.
In this Article
- Pancreatic cancer facts
- What does a pancreas do?
- What is cancer?
- What is pancreatic cancer? What are the types of pancreatic cancer?
- What are pancreatic cancer causes and risk factors?
- What are pancreatic cancer symptoms and signs?
- How is the diagnosis of pancreatic cancer made?
- How do health care professionals determine the stage of pancreatic cancer?
- What is the treatment for resectable pancreatic cancer?
- What is the treatment for locally advanced unresectable pancreatic cancer?
- What is the treatment for metastatic pancreatic cancer?
- What are the side effects of pancreatic cancer treatment?
- What is the survival rate with pancreatic cancer?
- What research is being done on pancreatic cancer?
- Is complimentary or alternative medicine effective in pancreatic cancer treatment?
- Is it possible to prevent pancreatic cancer?
- Where can people get support when coping with pancreatic cancer?
- Where can people find additional information about pancreatic cancer?
- Find a local Oncologist in your town
What are pancreatic cancer causes and risk factors?
About 53,670 cases of pancreatic cancer occur yearly in the United States. Most people who develop pancreatic cancer do so without any predisposing risk factors. However, perhaps the biggest risk factor is increasing age; being over the age of 60 puts an individual at greater risk. Rarely, there can be familial or hereditary genetic syndromes arising from genetic mutations that run in families and put individuals at higher risk, such as BRCA-2 and, to a lesser extent, BRCA-1 gene mutations. Familial syndromes are unusual, but it is important to let a doctor know if anyone else in the family has been diagnosed with cancer, especially pancreatic cancer. Additionally, certain behaviors or conditions are thought to slightly increase an individual's risk for developing pancreatic cancer. For example, African-Americans may be at greater risk as may individuals with close family members who have been previously diagnosed with pancreatic cancer. Other behaviors or conditions that may put people at risk include tobacco use, obesity, a sedentary lifestyle, a history of diabetes, chronic pancreatic inflammation (pancreatitis), and a fatty (or Western) diet. Prior stomach surgery may moderately increase one's risk as can certain chronic infections such as hepatitis B and H. pylori (a bacterial infection of the stomach lining). Certain drugs (sitagliptin [Januvia] and metformin and sitagliptin [Janumet]) have been linked to the development of pancreatic cancer. Some types of pancreatic cysts may put individuals at risk of developing pancreatic cancer. When pancreatic cancer begins, it usually starts in the cells that line the ducts of the pancreas and is termed pancreatic adenocarcinoma or pancreatic exocrine cancer. Despite the associated risks cited above, no identifiable cause is found in most people who develop pancreatic cancer.
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