Parafon Forte

Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 6/28/2021
Parafon Forte Side Effects Center

What Is Parafon Forte?

Parafon Forte (chlorzoxazone) is a muscle relaxant prescribed to treat musculoskeletal pain or injury. Parafon Forte is usually used in conjunction with rest and physical therapy. Parafon Forte is available in generic form.

What Are Side Effects of Parafon Forte?

Side effects of Parafon Forte may include:

  • drowsiness,
  • dizziness,
  • lightheadedness,
  • tired feeling,
  • restlessness,
  • upset stomach,
  • discolored urine,
  • skin rash,
  • bruising, or
  • headache.

Tell your doctor right away if you have any serious side effects of Parafon Forte including:

  • confusion,
  • black or bloody stools,
  • vomit that looks like coffee grounds,
  • easy bruising or bleeding, or
  • signs of infection (such as fever, persistent sore throat).

Dosage for Parafon Forte

Parafon Forte is dosed in 500 mg caplets, taken orally three or four times per day.

What Drugs, Substances, or Supplements Interact with Parafon Forte?

Parafon Forte may interact with cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, seizure medication, antidepressants or anti-anxiety medications. Parafon Forte may harm a fetus, and should be used only when clearly needed during pregnancy.

Parafon Forte During Pregnancy or Breastfeeding

Consult your physician if you are pregnant. It is not known whether this drug passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Parafon Forte Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


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Parafon Forte Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

  • a light-headed feeling, like you might pass out;
  • skin rash, itching, or redness;
  • liver problems--stomach pain (upper right side), loss of appetite, vomiting, fever, unusual tiredness, dark urine, or jaundice (yellowing of the skin or eyes); or
  • signs of stomach bleeding--bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Common side effects may include:

  • drowsiness;
  • dizziness; or
  • general ill feeling.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Parafon Forte (Chlorzoxazone)


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Parafon Forte Professional Information


Chlorzoxazone containing products are usually well tolerated. It is possible in rare instances that chlorzoxazone may have been associated with gastrointestinal bleeding. Drowsiness, dizziness, lightheadedness, malaise, or overstimulation may be noted by an occasional patient. Rarely, allergic-type skin rashes, petechiae, or ecchymoses may develop during treatment. Angioneurotic edema or anaphylactic reactions are extremely rare. There is no evidence that the drug will cause renal damage. Rarely, a patient may note discoloration of the urine resulting from a phenolic metabolite of chlorzoxazone. This finding is of no known clinical significance.

Read the entire FDA prescribing information for Parafon Forte (Chlorzoxazone)

© Parafon Forte Patient Information is supplied by Cerner Multum, Inc. and Parafon Forte Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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