Pathologic fracture: A bone broken, not by trauma alone, but so weakened by disease as to break with abnormal ease. Pathologic fractures are characteristic of metastatic lung and breast cancer and myeloma.

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Pathologic fracture: A bone broken, not by trauma alone, but so weakened by disease as to break with abnormal ease. Pathologic fractures are characteristic of metastatic lung and breast cancer and myeloma.