Paxil vs. Drizalma Sprinkle

Reviewed on 8/8/2019

Are Paxil and Drizalma Sprinkle the Same Thing?

Paxil (paroxetine hydrochloride) and Drizalma Sprinkle (duloxetine delayed-release capsules) are antidepressants used to treat depression and anxiety disorders.

Paxil is also used to treat panic attacks, obsessive-compulsive disorder (OCD), post-traumatic stress disorder, and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).

Drizalma Sprinkle is also used to treat diabetic peripheral neuropathic pain in adults and chronic musculoskeletal pain in adults.

Side effects of Paxil that are different from Drizalma Sprinkle include headache, nervousness, restlessness, dizziness, nasal irritation, sleep problems (insomnia), weight changes, decreased sex drive, impotence, difficulty having an orgasm, yawning, and ringing in the ears.

Drizalma Sprinkle and Paxil are different types of antidepressants. Drizalma Sprinkle is a serotonin and norepinephrine reuptake inhibitor (SNRI) and Paxil is a selective serotonin reuptake inhibitor (SSRI).

Side effects of Drizalma Sprinkle and Paxil that are similar include nausea, dry mouth, drowsiness, and constipation.

Side effects of Drizalma Sprinkle that are different from Paxil include decreased appetite and increased sweating.

Both Drizalma Sprinkle and Paxil may interact with alcohol, triptans, other antidepressants, fentanyl, tramadol, tryptophan, St. John's wort, cimetidine, nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin, blood thinners, and theophylline.

Paxil may also interact with cold or allergy medicines, sedatives, narcotics, sleeping pills, muscle relaxers, medicines for seizures or anxiety, fosamprenavir, ritonavir, tamoxifen, theophylline, heart medications, and medicines to treat psychiatric disorders.

Do not stop using Paxil suddenly, or you could have unpleasant withdrawal symptoms.

Drizalma Sprinkle may also interact with monoamine oxidase inhibitors (MAOIs), fentanyl, lithium, buspirone, amphetamines, ciprofloxacin, enoxacin, warfarin, quinidine, phenothiazines, type 1C antiarrhythmics, aluminum-and magnesium-containing antacids, famotidine, proton pump inhibitors (PPIs), caffeine, centrally acting CNS drugs, and highly plasma protein binding drugs.

What Are Possible Side Effects of Paxil?

Common side effects of Paxil include:

  • headache,
  • nervousness,
  • restlessness,
  • drowsiness,
  • dizziness,
  • nasal irritation,
  • sleep problems (insomnia),
  • nausea,
  • constipation,
  • weight changes,
  • decreased sex drive,
  • impotence,
  • difficulty having an orgasm,
  • dry mouth,
  • yawning, or
  • ringing in the ears.

Call your doctor immediately if you are experiencing suicidal thoughts.

What Are Possible Side Effects of Drizalma Sprinkle?

Common side effects of Drizalma Sprinkle include:

  • nausea,
  • dry mouth,
  • drowsiness,
  • constipation,
  • decreased appetite, and
  • increased sweating

What Is Paxil?

Paxil (paroxetine hydrochloride) is a selective serotonin reuptake inhibitor (SSRI) antidepressant used to treat depression, panic attacks, obsessive-compulsive disorder (OCD), anxiety disorders, post-traumatic stress disorder, and a severe form of premenstrual syndrome (premenstrual dysphoric disorder).

What Is Drizalma Sprinkle?

Drizalma Sprinkle (duloxetine delayed-release capsules) is a serotonin and norepinephrine reuptake inhibitor (SNRI) indicated for major depressive disorder in adults, generalized anxiety disorder in adults and pediatric patients ages 7 years to 17 years old, diabetic peripheral neuropathic pain in adults, and chronic musculoskeletal pain in adults.

SLIDESHOW

Learn to Spot Depression: Symptoms, Warning Signs, Medication See Slideshow

What Drugs Interact With Paxil?

Paxil may interact with cold or allergy medicines, sedatives, narcotics, sleeping pills, muscle relaxers, medicines for seizures or anxiety, other antidepressants, nonsteroidal anti-inflammatory drugs (NSAIDs), blood thinners, cimetidine, tramadol, L-tryptophan, or medicines to treat migraines.

Paxil may also interact with fentanyl, fosamprenavir, ritonavir, St. John's wort, tamoxifen, theophylline, heart medications, or medicines to treat psychiatric disorders.

You may have withdrawal symptoms (such as agitation, dizziness, numbness or tingling, ringing in your ears, confusion, or behavior changes) after you stop taking Paxil.

What Drugs Interact With Drizalma Sprinkle?

Drizalma Sprinkle may interact with monoamine oxidase inhibitors (MAOIs), triptans, tricyclic antidepressants, other SNRIs or SSRIs, fentanyl, lithium, tramadol, tryptophan, buspirone, amphetamines, St. John's wort, cimetidine, ciprofloxacin, enoxacin, nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin, warfarin, quinidine, phenothiazines, type 1C antiarrhythmics, aluminum-and magnesium-containing antacids, famotidine, proton pump inhibitors (PPIs), theophylline, caffeine, centrally acting CNS drugs, highly plasma protein binding drugs, and alcohol. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Drizalma Sprinkle; third trimester use may increase risk of symptoms of poor adaptation (respiratory distress, temperature instability, feeding difficulty, low muscle tone, tremor, irritability) in newborns. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to antidepressants during pregnancy. Drizalma Sprinkle passes into breast milk but its effects on nursing infants are unknown. Consult your doctor before breastfeeding.

How Should Paxil Be Taken?

The recommended initial dose of Paxil depends on the condition being treated and ranges from 20 mg/day to 50 mg/day.

How Should Drizalma Sprinkle Be Taken?

The dose of Drizalma Sprinkle is 60 mg daily for most conditions.

QUESTION

Depression is a(n) __________ . See Answer
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References


FDA. Paxil Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/020031s067,020710s031.pdf

FDA. Drizalma Sprinkle Product Information.

https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/212516s000lbl.pdf

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