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Pepcid vs. Zantac

Are Pepcid and Zantac the Same Thing?

Pepcid (famotidine) and Zantac (ranitidine hydrochloride) are H2-blockers used to treat and prevent recurrence of stomach and duodenal ulcers. Pepcid is also useful in managing heartburn, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome.

Pepcid and Zantac are available over-the-counter (OTC) and in generic form.

What Are Possible Side Effects of Pepcid?

Common side effects of Pepcid include:

What Are Possible Side Effects of Zantac?

Common side effects of Zantac include:

  • constipation,
  • diarrhea,
  • fatigue,
  • headache (may be severe),
  • drowsiness,
  • dizziness,
  • sleep problems (insomnia),
  • decreased sex drive,
  • impotence,
  • difficulty having an orgasm,
  • muscle pain,
  • stomach pain,
  • nausea,
  • vomiting,
  • diarrhea,
  • constipation,
  • or swollen or tender breasts (in men).

What is Pepcid?

Pepcid (famotidine) is an H2-blocker used to treat and prevent recurrence of stomach and duodenal ulcers. Pepcid is also useful in managing heartburn, gastroesophageal reflux disease and Zollinger-Ellison syndrome. Pepcid is available as a generic drug.

What is Zantac?

Zantac (ranitidine hydrochloride) is a H2 (histamine-2) receptor blocker used for treating and preventing ulcers in the duodenum and stomach. Zantac is also used for treating:

  • heartburn,
  • erosive esophagitis,
  • and Zollinger Ellison syndrome.

SLIDESHOW

Digestive Disorders: Common Misconceptions See Slideshow

What Drugs Interact With Pepcid?

Pepcid may interact with atazanavir, itraconazole, ketoconazole, or aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs). Tell your doctor all medications and supplements you use.

What Drugs Interact With Zantac?

Zantac may interact with ketoconazole, atazanavir, and blood thinners such as warfarin.

Zantac may also interact with triazolam, procainamide, riazolam, midazolam, glipizide, delavirdine, and gefitinib.

How Should Pepcid Be Taken?

Pepcid (famotidine) dosage depends on the condition being treated.

How Should Zantac Be Taken?

Zantac is available in tablet, syrup, and injectable formulations.

  • adults and children 12 years and over:
    • to relieve symptoms, swallow 1 tablet with a glass of water
    • to prevent symptoms, swallow 1 tablet with a glass of water 30 to 60 minutes before eating food or drinking beverages that cause heartburn
    • can be used up to twice daily (do not take more than 2 tablets in 24 hours)
  • children under 12 years: ask a doctor

Other Information

  • do not use if printed foil under bottle cap is open or torn (bottles)
  • do not use if individual blister unit is open or torn (blisters)
  • do not use if individual foil packet is open or torn (pouch)
  • store at 20°-25°C (68°-77°F)
  • avoid excessive heat or humidity
  • this product is sodium and sugar free
Disclaimer

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Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.

Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.

The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.

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References
SOURCE:
McNeil Consumer Pharmaceuticals Co. Pepcid Consumer Information.
www.pepcid.com
Sanofi. Zantac Consumer Product Information.
https://www.zantacotc.com

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