Periogard

Last updated on RxList: 1/31/2019
Periogard Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 1/31/2019

Periogard (chlorhexidine gluconate oral rinse, 0.12%) is an antiseptic indicated for use between dental visits as part of a professional program for the treatment of gingivitis as characterized by redness and swelling of the gingivae, including gingival bleeding upon probing. Common side effects of Periogard include:

  • an increase in staining of teeth and other oral surfaces,
  • an increase in tartar,
  • changes in taste,
  • oral irritation, and
  • local allergy-type symptoms

The recommended use of PerioGard is twice daily rinsing for 30 seconds, morning and evening after tooth brushing. The usual dosage is 15 ml (marked in cap) of undiluted PerioGard. Periogard may interact with other drugs. Tell your doctor all medications and supplements you use. Tell your doctor if you are pregnant or plan to become pregnant before using Periogard; it is unknown how it would affect a fetus. It is unknown if Periogard passes into breast milk. Consult your doctor before breastfeeding.

Our Periogard (chlorhexidine gluconate oral rinse, 0.12%) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

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Periogard Consumer Information

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Chlorhexidine gluconate can cause a rare but serious allergic reaction that may be life-threatening. Get emergency medical help if you have any of these signs of an allergic reaction: hives, severe skin rash; wheezing, difficult breathing; cold sweats, feeling light-headed; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • white patches or sores inside your mouth or on your lips;
  • mouth ulcers; or
  • swelling of your salivary glands (underneath your jaws).

Common side effects may include:

  • mouth irritation;
  • tooth staining;
  • dry mouth;
  • unusual or unpleasant taste in your mouth; or
  • decreased taste sensation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Periogard (Chlorhexidine Gluconate Oral Rinse)

SLIDESHOW

Mouth Problems: TMJ, Canker Sores, Painful Gums and More See Slideshow
Periogard Professional Information

SIDE EFFECTS

The most common side effects associated with chlorhexidine gluconate oral rinse USP, 0.12% are: 1) an increase in staining of teeth and other oral surfaces; 2) an increase in calculus formation; and 3) an alteration in taste perception; see WARNINGS AND PRECAUTIONS. Oral irritation and local allergytype symptoms have been spontaneously reported as side effects associated with use of chlorhexidine gluconate oral rinse. The following oral mucosal side effects were reported during placebo-controlled adult clinical trials: aphthous ulcer, grossly obvious gingivitis, trauma, ulceration, erythema, desquamation, coated tongue, keratinization, geographic tongue, mucocele, and short frenum. Each occurred at frequency of less than 1%.

Among post-marketing reports, the most frequently reported oral mucosal symptoms associated with chlorhexidine gluconate oral rinse USP, 0.12% are stomatitis, gingivitis, glossitis, ulcer, dry mouth, hypesthesia, glossal edema, and paresthesia.

Minor irritation and superficial desquamation of the oral mucosa have been noted in patients using chlorhexidine gluconate oral rinse.

There have been cases of parotid gland swelling and inflammation of the salivary glands (sialadenitis) reported in patients using chlorhexidine gluconate oral rinse.

Read the entire FDA prescribing information for Periogard (Chlorhexidine Gluconate Oral Rinse)

© Periogard Patient Information is supplied by Cerner Multum, Inc. and Periogard Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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