Brand Names: Acticlate, Adoxa, Alodox, Avidoxy, Doryx, Doryx MPC, Doxy Lemmon, Doxy-Caps, Doxy-D, Mondoxyne NL, Monodox, Morgidox, Morgidox 1x100mg, Morgidox 2x100mg, Okebo, Oracea, Oraxyl, Periostat, Targadox, Vibra-Tabs, Vibramycin, Vibramycin Calcium, Vibramycin Monohydrate
Generic Name: doxycycline (oral/injection)
- What is doxycycline?
- What are the possible side effects of doxycycline?
- What is the most important information I should know about doxycycline?
- What should I discuss with my healthcare provider before taking doxycycline?
- How should I take doxycycline?
- What happens if I miss a dose?
- What happens if I overdose?
- What should I avoid while taking doxycycline?
- What other drugs will affect doxycycline?
- Where can I get more information?
What is doxycycline?
Doxycycline is used to treat many different bacterial infections, such as acne, urinary tract infections, intestinal infections, eye infections, gonorrhea, chlamydia, periodontitis (gum disease), and others.
Doxycycline may also be used for purposes not listed in this medication guide.
What are the possible side effects of doxycycline?
Get emergency medical help if you have signs of an allergic reaction (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning in your eyes, skin pain, red or purple skin rash that spreads and causes blistering and peeling).
Seek medical treatment if you have a serious drug reaction that can affect many parts of your body. Symptoms may include: skin rash, fever, swollen glands, flu-like symptoms, muscle aches, severe weakness, unusual bruising, or yellowing of your skin or eyes. This reaction may occur several weeks after you began using doxycycline.
Call your doctor at once if you have:
- severe stomach pain, diarrhea that is watery or bloody;
- throat irritation, trouble swallowing;
- chest pain, irregular heart rhythm, feeling short of breath;
- little or no urination;
- low white blood cell counts--fever, chills, swollen glands, body aches, weakness, pale skin, easy bruising or bleeding;
- increased pressure inside the skull--severe headaches, ringing in your ears, dizziness, nausea, vision problems, pain behind your eyes; or
- signs of liver or pancreas problems--loss of appetite, upper stomach pain (that may spread to your back), tiredness, nausea or vomiting, fast heart rate, dark urine, jaundice (yellowing of the skin or eyes).
Common side effects may include:
- nausea, vomiting, upset stomach, loss of appetite;
- mild diarrhea;
- skin rash or itching;
- darkened skin color; or
- vaginal itching or discharge.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What is the most important information I should know about doxycycline?
You should not take this medicine if you are allergic to any tetracycline antibiotic.
Children younger than 8 years old should use doxycycline only in cases of severe or life-threatening conditions. This medicine can cause permanent yellowing or graying of the teeth in children
Using doxycycline during pregnancy could harm the unborn baby or cause permanent tooth discoloration later in the baby's life.
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What should I discuss with my healthcare provider before taking doxycycline?
You should not take this medicine if you are allergic to doxycycline or other tetracycline antibiotics such as demeclocycline, minocycline, tetracycline, or tigecycline.
Tell your doctor if you have ever had:
- liver disease;
- kidney disease;
- asthma or sulfite allergy;
- increased pressure inside your skull; or
- if you also take isotretinoin, seizure medicine, or a blood thinner such as warfarin (Coumadin).
Taking this medicine during pregnancy may affect tooth and bone development in the unborn baby. Taking doxycycline during the last half of pregnancy can cause permanent tooth discoloration later in the baby's life. Tell your doctor if you are pregnant or if you become pregnant.
Doxycycline can make birth control pills less effective. Ask your doctor about using a non-hormonal birth control (condom, diaphragm with spermicide) to prevent pregnancy.
Doxycycline can pass into breast milk and may affect bone and tooth development in a nursing infant. Do not breastfeed while you are taking doxycycline.
Doxycycline can cause permanent yellowing or graying of the teeth in children younger than 8 years old. Children should use doxycycline only in cases of severe or life-threatening conditions such as anthrax or Rocky Mountain spotted fever. The benefit of treating a serious condition may outweigh any risks to the child's tooth development.
How should I take doxycycline?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Take doxycycline with a full glass of water. Drink plenty of liquids while you are taking doxycycline.
Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.
Most brands of doxycyline may be taken with food or milk if the medicine upsets your stomach.
Different brands of doxycycline may have different instructions about taking them with or without food.
Take Oracea on an empty stomach, at least 1 hour before or 2 hours after a meal.
You may need to split a doxycycline tablet to get the correct dose. Follow your doctor's instructions.
Swallow a delayed-release capsule or tablet whole. Do not crush, chew, break, or open it.
Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. If you do not have a dose-measuring device, ask your pharmacist for one.
If you take doxycycline to prevent malaria: Start taking the medicine 1 or 2 days before entering an area where malaria is common. Continue taking the medicine every day during your stay and for at least 4 weeks after you leave the area.
Doxycycline is usually given by injection only if you are unable to take the medicine by mouth. A healthcare provider will give you this injection as an infusion into a vein.
Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. Doxycycline will not treat a viral infection such as the flu or a common cold.
Store at room temperature away from moisture, heat, and light.
Throw away any unused medicine after the expiration date on the label has passed. Using expired doxycycline can cause damage to your kidneys.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking doxycycline?
Do not take iron supplements, multivitamins, calcium supplements, antacids, or laxatives within 2 hours before or after taking doxycycline.
Avoid taking any other antibiotics with doxycycline unless your doctor has told you to.
Doxycycline could make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Antibiotic medicines can cause diarrhea, which may be a sign of a new infection. If you have diarrhea that is watery or bloody, call your doctor. Do not use anti-diarrhea medicine unless your doctor tells you to.
What other drugs will affect doxycycline?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
Other drugs may affect doxycycline, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Where can I get more information?
Your pharmacist can provide more information about doxycycline.