Medical Editor: John P. Cunha, DO, FACOEP
Phentolamine Mesylate for Injection is an antihypertensive indicated for the prevention or control of hypertensive (high blood pressure) episodes that may occur in a patient with pheochromocytoma as a result of stress or manipulation during preoperative preparation and surgical excision, for the prevention or treatment of dermal necrosis and sloughing following intravenous administration or extravasation of norepinephrine, and for the diagnosis of pheochromocytoma by the phentolamine blocking test. Phentolamine mesylate for injection is available in generic form. Common side effects of phentolamine mesylate for injection include:
- acute and prolonged hypotensive episodes
- fast heart rate
- cardiac arrhythmias
- dizziness upon standing (orthostatic hypotension)
- stuffy nose
For preoperative reduction of elevated blood pressure, a dose of 5 mg of phentolamine mesylate (1 mg for children) is injected intravenously or intramuscularly 1 or 2 hours before surgery. Phentolamine mesylate may interact with other drugs. Tell your doctor all medications and supplements you use. During pregnancy, phentolamine mesylate should be used only if prescribed. It is unknown if this drug is excreted in human milk. Consult your doctor before breastfeeding.
Our Phentolamine Mesylate for Injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Acute and prolonged hypotensive episodes, tachycardia, and cardiac arrhythmias have been reported. In addition, weakness, dizziness, flushing, orthostatic hypotension, nasal stuffiness, nausea, vomiting, and diarrhea may occur.
Read the entire FDA prescribing information for Phentolamine Mesylate for Injection (Phentolamine Mesylate)
© Phentolamine Mesylate for Injection Patient Information is supplied by Cerner Multum, Inc. and Phentolamine Mesylate for Injection Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.