- Are Pradaxa and Plavix the Same Thing?
- What Are Possible Side Effects of Plavix?
- What Are Possible Side Effects of Pradaxa?
- What is Plavix?
- What is Pradaxa?
- What Drugs Interact with Plavix?
- What Drugs Interact with Pradaxa?
- How Should Plavix Be Taken?
- How Should Pradaxa Be Taken?
Are Pradaxa and Plavix the Same Thing?
Plavix (clopidogrel bisulfate) and Pradaxa (dabigatran) are anticoagulants (blood thinners) that inhibit aspects of blood clotting and are used to treat patients with acute coronary syndrome, heart attack (myocardial infarction), peripheral vascular disease, and ischemic strokes.
What Are Possible Side Effects of Plavix?
Common side effects of Plavix include:
- easy bleeding and bruising;
- pain, redness, warmth, irritation, or skin changes where the medicine was injected;
- itching of your feet; or
- bluish-colored skin.
Thrombocytopenia, pradaxa-induced thrombocytopenia (HIT) and pradaxa-induced thrombocytopenia and thrombosis (HITT) are serious side effects of pradaxa.
What Are Possible Side Effects of Pradaxa?
Common side effects of Pradaxa include:
- bruising and minor bleeding (such as nosebleeds and bleeding from cuts),
- abdominal or stomach pain,
- stomach upset,
- skin rash, or
Tell your doctor if you have serious side effects of Pradaxa including:
- severe heartburn,
- nausea, or
What is Plavix?
Plavix (clopidogrel bisulfate) is a thienopyridine class of drug that inhibits platelet aggregation and thus inhibits aspects of blood clotting used to treat patients with acute coronary syndrome, myocardial infarction (MI), peripheral vascular disease and some stroke (ischemic type) patients. Plavix is available in generic form.
What is Pradaxa?
Pradaxa (dabigatran) is an anticoagulant that works by blocking the clotting protein thrombin. Pradaxa is used to prevent blood clots from forming because of a certain irregular heart rhythm (atrial fibrillation). Preventing these blood clots helps to reduce the risk of a stroke.
What Drugs Interact With Plavix?
Plavix may interact with other blood thinners, aspirin, or nonsteroidal anti-inflammatory drugs (NSAIDs).
Plavix may also interact with armodafinil, modafinil, fluoxetine, fluvoxamine, gemfibrozil, isoniazid, cancer medications, stomach acid reducers, antifungals, HIV medications, or seizure medications.
What Drugs Interact With Pradaxa?
Pradaxa may interact with other medicines to treat or prevent blood clots, aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), antifungals, or HIV/AIDS medications.
Pradaxa may also interact with antibiotics, St. John's wort, heart or blood pressure medications, or medicines used to prevent organ transplant rejection.
How Should Plavix Be Taken?
Plavix is supplied as 75 and 300 mg tablets. For acute coronary syndrome with a non-ST elevation MI, the initial recommended dose is 300 mg, followed by a 75 mg dose per day; for ST elevation MIs, the initial and continuing dose is 75 mg per day. The recommended dose is 75 mg per day for patient with a history of MI, stroke, or peripheral vascular disease. Many doctors may choose to add an aspirin per day along with the Plavix dose in both non-ST elevation and ST elevation MIs as well as to stroke and peripheral vascular disease patients.
How Should Pradaxa Be Taken?
The usual recommended dose of Pradaxa is 150 mg taken orally, twice daily Pradaxa is administered in capsule form.
Healthy Heart Resources
Health Solutions From Our Sponsors
All drug information provided on RxList.com is sourced directly from drug monographs published by the U.S. Food and Drug Administration (FDA).
Any drug information published on RxList.com regarding general drug information, drug side effects, drug usage, dosage, and more are sourced from the original drug documentation found in its FDA drug monograph.
Drug information found in the drug comparisons published on RxList.com is primarily sourced from the FDA drug information. The drug comparison information found in this article does not contain any data from clinical trials with human participants or animals performed by any of the drug manufacturers comparing the drugs.
The drug comparisons information provided does not cover every potential use, warning, drug interaction, side effect, or adverse or allergic reaction. RxList.com assumes no responsibility for any healthcare administered to a person based on the information found on this site.
As drug information can and will change at any time, RxList.com makes every effort to update its drug information. Due to the time-sensitive nature of drug information, RxList.com makes no guarantees that the information provided is the most current.
Any missing drug warnings or information does not in any way guarantee the safety, effectiveness, or the lack of adverse effects of any drug. The drug information provided is intended for reference only and should not be used as a substitute for medical advice.
If you have specific questions regarding a drug’s safety, side effects, usage, warnings, etc., you should contact your doctor or pharmacist, or refer to the individual drug monograph details found on the FDA.gov or RxList.com websites for more information.
You may also report negative side effects of prescription drugs to the FDA by visiting the FDA MedWatch website or calling 1-800-FDA-1088.
Plavix Product Information.
Pradaxa Product Information.