Plenity vs. Saxenda

Reviewed on 12/16/2020

Are Plenity and Saxenda the Same Thing?

Plenity (cellulose and citric acid) and Saxenda (liraglutide [rDNA origin]) Injection are used to help patients manage their weight and when used in conjunction with diet and exercise.

Plenity is indicated to aid in weight management in overweight and obese adults with a Body Mass Index (BMI) of 25-40 kg/m2.

Saxenda is in adult patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obese), or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia).

Plenity and Saxenda belong to different drug classes. Plenity is a medication that promotes fullness and Saxenda is an analog of human GLP-1 and acts as a GLP-1 receptor agonist.

Side effects of Plenity and Saxenda that are similar include abdominal or stomach pain or upset, bloating, constipation, diarrhea, indigestion, gas, belching, gastroesophageal reflux disease (GERD), and vomiting.

Side effects of Plenity that are different from Saxenda include abdominal distension, irregular bowel movements, changes in frequency and consistency of bowel movements, cramping, and difficulty swallowing.

Side effects of Saxenda that are different from Plenity include nausea, low blood sugar (hypoglycemia), decreased appetite, headache, dizziness, fatigue, urinary tract infection (UTI), dry mouth, changes in taste, injection site reactions or redness, lack of energy or weakness, gastroenteritis, anxiety, and insomnia.

Both Plenity and Saxenda may interact with other oral medications taken at the same time.

What Are Possible Side Effects of Plenity?

Common side effects of Plenity are mild and include:

  • abdominal distension,
  • abdominal pain,
  • bloating,
  • irregular bowel movements,
  • changes in frequency and consistency of bowel movements,
  • constipation,
  • cramping,
  • diarrhea,
  • indigestion,
  • difficulty swallowing,
  • belching,
  • gas,
  • gastroesophageal reflux disease (GERD), and
  • vomiting

What Are Possible Side Effects of Saxenda?

Common side effects of Saxenda include:

SLIDESHOW

Surprising Causes of Weight Gain See Slideshow

What Is Plenity?

Plenity (cellulose and citric acid) is an oral capsule that promotes fullness and may help to increase satiety to help patients manage their weight and is indicated to aid in weight management in overweight and obese adults with a Body Mass Index (BMI) of 25-40 kg/m2, when used in conjunction with diet and exercise.

What Is Saxenda?

Saxenda (liraglutide [rDNA origin]) Injection is an analog of human GLP-1 and acts as a GLP-1 receptor agonist used for as an adjunct to a reduced-calorie diet and increased physical activity for chronic weight management in adult patients with an initial body mass index (BMI) of 30 kg/m2 or greater (obese), or 27 kg/m2 or greater (overweight) in the presence of at least one weight-related comorbid condition (e.g., hypertension, type 2 diabetes mellitus, or dyslipidemia).

What Drugs Interact With Plenity?

Plenity may interact with other oral medications taken at the same time. Tell your doctor all medications and supplements you use.

What Drugs Interact With Saxenda?

Saxenda may interact with other oral medications taken at the same time. Tell your doctor all medications and supplements you use.

How Should Plenity be Taken?

Plenity is supplied in double blister packs that, together, provide the two doses patients take daily. Each individual blister pack holds a single dose of three (3) capsules, to be administered with water before lunch and dinner.

How Should Saxenda be Taken?

The recommended dosage of Saxenda is 3 mg daily.

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References
Gelesis. Plenity Product Information

https://www.myplenity.com/

Novo Nordisk. Saxenda Product Information.

https://qsymia.com/

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