Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 1/31/2023

Drug Summary

What Is Polmon?

Polmon (dexchlorpheniramine maleate oral solution) is an antihistamine used to treat allergy symptoms such as sneezing, congestion, runny nose, watery eyes, itching, hives, skin swelling, and rash. Polmon is available in generic form.

What Are Side Effects of Polmon?

Polmon may cause serious side effects including:

  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • mental or mood changes,
  • restlessness,
  • confusion,
  • trouble urinating,
  • fast, pounding or irregular heartbeat,
  • severe headache,
  • slurred speech,
  • arm or leg weakness,
  • trouble walking,
  • loss of coordination,
  • feeling unsteady,
  • very stiff (rigid) muscles,
  • high fever,
  • profuse sweating,
  • tremors,
  • sudden vision loss,
  • blurred vision,
  • tunnel vision,
  • eye pain or swelling,
  • seeing halos around lights,
  • fluttering in the chest,
  • shortness of breath,
  • sudden dizziness,
  • lightheadedness, and
  • fainting

Get medical help right away, if you have any of the symptoms listed above.

Common side effects of Polmon include:

Seek medical care or call 911 at once if you have the following serious side effects:

  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheadedness, or passing out;
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Polmon

The recommended dose of Polmon for adults and children 12 years of age and older is 2 mg (1 teaspoonful).

What Drugs, Substances, or Supplements Interact with Polmon?

Polmon may interact with MAO inhibitors. Tell your doctor all medications and supplements you use.

Polmon During Pregnancy or Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Polmon; it is unknown how it would affect a fetus. Breastfeeding is not recommended while using Polmon.

Additional Information

Our Polmon (dexchlorpheniramine maleate oral solution) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

Drug Description


Each 5 mL (teaspoonful) contains :

Dexchlorpheniramine Maleate, USP ............. 2 mg

Dexchlorpheniramine Maleate, USP, an antihistamine agent, is a white, odorless crystalline powder that is freely soluble in water. The molecular formula is C16H19ClN2 • C4H4O4, designated chemically as (+)-2-[p-Chloro-α-[2-(dimethylamino)ethyl]benzyl]pyridine maleate (1:1).

POLMON (Dexchlorpheniramine Maleate Oral Solution, USP) Structural Formula - Illustration

M.W. = 390.86

Inactive Ingredients

Citric acid, cherry flavoring, FD&C Red No. 40, glycerin, menthol, methylparaben, propylene glycol, propylparaben, purified water, sodium citrate dihydrate, and sugar.

Indications & Dosage


Perennial and seasonal allergic rhinitis

Vasomotor rhinitis

Allergic conjunctivitis due to inhalant allergens and foods

Mild, uncomplicated allergic skin manifestations of urticaria and angioedema

Amelioration of allergic reactions to blood or plasma


As therapy for anaphylactic reactions adjunctive to epinephrine and other standard measures after the acute manifestations have been controlled.



Recommended Dosage

Adults and Children 12 years of age and older: 2 mg (1 teaspoonful)

Children 6 to 11 years: 1 mg (½ teaspoonful)

Children 2 to 5 years: 0.5 mg (1/4 teaspoonful)

Doses are generally given every 4 to 6 hours.


POLMON Oral Solution is supplied as a red colored, cherry flavored liquid in the following sizes:

4 fl oz (118 mL), NDC 64543-600-04
16 fl oz (473 mL), NDC 64543-600-16

Storage And Handling

Store at 20° to 25°C (68° to 77°F) [see USP Controlled Room Temperature].

Dispense in a tight, light-resistant container as defined in the USP, with child-resistant closure.

Manufactured For: Capellon Pharmaceuticals, LLCFort Worth, TX 76118. Revised: Nov 2020

Side Effects & Drug Interactions


  1. General: Urticaria, drug rash, anaphylactic shock, photosensitivity, excessive perspiration, chills, dryness of mouth, nose and the throat.
  2. Cardiovascular System: Hemolytic anemia, thrombocytopenia, agranulocytosis.
  3. Hematologic System: Hemolytic anemia, thrombocytopenia, agranulocytosis.
  4. Nervous System: Sedation, sleepiness, dizziness, disturbed coordination, fatigue, confusion, restlessness, excitation, nervousness, tremor, irritability, insomnia, euphoria, paresthesias, blurred vision, diplopia, vertigo, tinnitus, acute labyrinthitis, hysteria, neuritis, convulsions.
  5. G.I. System: Epigastric distress, anorexia, nausea, vomiting, diarrhea, constipation.
  6. G.U. System: Urinary frequency, difficult urination, urinary retention, early menses.
  7. Respiratory System: Thickening of bronchial secretions, tightness of chest and wheezing, nasal stuffiness.


MAO inhibitors prolong and intensify the anticholinergic (drying) effects of antihistamines.

Warnings & Precautions


Antihistamines should be used with considerable caution in patients with:

Stenosing peptic ulcer

Pyloroduodenal obstruction

Symptomatic prostatic hypertrophy

Bladder neck obstruction

Use In Children

In infants and children, especially, antihistamines in overdosage may cause hallucinations, convulsions, or death.

As in adults, antihistamines may diminish mental alertness in children. In the young child, particularly, they may produce excitation.

Use In Pregnancy

Experience with this drug in pregnant women is inadequate to determine whether there exists a potential for harm to the developing fetus.

Use With CNS Depressants

POLMON Oral Solution has additive effects with alcohol and other CNS depressants (hypnotics, sedatives, tranquilizers, etc.).

Use In Activities Requiring Mental Alertness

Patients should be warned about engaging in activities requiring mental alertness such as driving a car or operating appliances, machinery, etc.

Use In The Elderly (approximately 60 years or older)

Antihistamines are more likely to cause dizziness, sedation, and hypotension in elderly patients.


POLMON Oral Solution has an atropine-like action and, therefore, should be used with caution in patients with:

History of bronchial asthma
Increased intraocular pressure
Cardiovascular disease

Overdose & Contraindications


Antihistamine overdosage reactions may vary from central nervous system depression to stimulation. Stimulation is particularly likely in children. Atropine-like signs and symptoms—dry mouth, fixed, dilated pupils, flushing, and gastrointestinal symptoms may also occur.

If vomiting has not occurred spontaneously the patient should be induced to vomit. This is best done by having the patient drink a glass of water or milk after which the patient should be made to gag. Precautions against aspiration must be taken, especially in infants and children.

Saline cathartics, such as milk of magnesia, draw water into the bowel by osmosis and therefore, are valuable for their action in rapid dilution of bowel content.

Stimulants should not be used.

Vasopressors may be used to treat hypotension.


Use In Newborn Or Premature Infants

This drug should not be used in newborn or premature infants.

Use In Nursing Mothers

Because of the higher risk of antihistamines for infants generally and for newborns and prematures in particular, antihistamine therapy is contraindicated in nursing mothers.

Use In Lower Respiratory Disease

Antihistamines should NOT be used to treat lower respiratory tract symptoms including asthma.

Antihistamines are also contraindicated in the following conditions:

  • Hypersensitivity to dexchlorpheniramine maleate or other antihistamines of similar chemical structure Monoamine oxidase inhibitor therapy (See DRUG INTERACTION section)
Clinical Pharmacology


Dexchlorpheniramine maleate is an antihistamine with anticholinergic (drying) and sedative side effects. Antihistamines appear to compete with histamine for cell receptor sites on effector cells.

Medication Guide


No information provided. Please refer to the WARNINGS AND PRECAUTIONS sections.

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