Medical Editor: John P. Cunha, DO, FACOEP
Poly-Pred (prednisolone acetate, neomycin sulfate, polymyxin B sulfate ophthalmic suspension) is a combination of a steroid and antibiotics used to treat bacterial infections of the eyes. The brand name Poly-Pred is discontinued, but generic versions may be available. Common side effects of Poly-Pred (prednisolone acetate, neomycin sulfate, polymyxin B sulfate ophthalmic suspension) include:
- stinging/burning of the eyes for 1 to 2 minutes when this medication is applied
- eye irritation
- blurred vision
- eyelid itching
- eyelid swelling, or
- sensitivity to light
The dose of Poly-Pred to treat the eye: Instill 1 or 2 drops every 3 or 4 hours, or more frequently as required. To treat the eyelids: Instill 1 or 2 drops in the eye every 3 to 4 hours, close the eye and rub the excess on the lids and lid margins. Poly-Pred may interact with other eye medications, or oral steroids. Tell your doctor all medications and supplements you use. During pregnancy, Poly-Pred should be used only when prescribed. This drug passes into breast milk. Consult your doctor before breastfeeding.
Our Poly-Pred (prednisolone acetate, neomycin sulfate, polymyxin B sulfate ophthalmic suspension) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In the US -
Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
In Canada - Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.
Read the entire patient information overview for Poly-Pred (Prednisolone,Neomycin and Polymyxin B)
Adverse reactions have occurred with steroid/anti-infective combination drugs which can be attributed to the steroid component, the anti-infective component, or the combination. Exact incidence figures are not available since no denominator of treated patients is available.
Reactions occurring most often from the presence of the anti-infective ingredients are allergic sensitizations including itching, swelling, and conjunctival erythema (see WARNINGS). More serious hypersensitivity reactions, including anaphylaxis, have been reported rarely. The reactions due to the steroid component in decreasing order of frequency are: elevation of intraocular pressure (IOP) with possible development of glaucoma, and infrequent optic nerve damage; posterior subcapsular cataract formation; and delayed wound healing.
Corticosteroid-containing preparations have also been reported to cause perforation of the globe. Keratitis, conjunctivitis, corneal ulcers, and conjunctival hyperemia have occasionally been reported following local use of steroids.
Secondary infection: The development of secondary infection has occurred after use of combinations containing steroids and antimicrobials. Fungal infections of the cornea are particularly prone to develop coincidentally with long-term applications of steroids. The possibility of fungal invasion must be considered in any persistent corneal ulceration where steroid treatment has been used.
Read the entire FDA prescribing information for Poly-Pred (Prednisolone,Neomycin and Polymyxin B)
© Poly-Pred Patient Information is supplied by Cerner Multum, Inc. and Poly-Pred Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.
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