Prednisolone Oral Solution

Last updated on RxList: 4/25/2018
Prednisolone Oral Solution Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 4/25/2018

Prednisolone sodium (prednisolone sodium phosphate oral solution) is a corticosteroid used to treat a wide variety of conditions including allergies, skin conditions, edema, endocrine disorders, ulcerative colitis, blood disorders, cancer, multiple sclerosis, eye diseases, lung diseases, and rheumatic diseases. Prednisolone sodium phosphate oral solution may be available in generic form. Common side effects of prednisolone sodium phosphate oral solution include:

The initial dosage of prednisolone sodium phosphate oral solution may vary from 5 mL to 60 mL (5 to 60 mg prednisolone base) per day depending on the disease being treated. Prednisolone sodium may interact with barbiturates, phenytoin, ephedrine, rifampin, cyclosporine, estrogens, ketoconazole, warfarin, aspirin or other non-steroidal anti-inflammatory drugs (NSAIDs), diuretics, amphotericin-B, digitalis, anticholinesterase drugs, certain vaccines, and anti-diabetic medications. Tell your doctor all medications and supplements you use and all vaccines you recently received. During pregnancy, prednisolone sodium should be used only if prescribed. Prednisolone sodium passes into breast milk and may harm a nursing baby. Consult your doctor before breastfeeding.

Our Prednisolone sodium (prednisolone sodium phosphate oral solution) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

Asthma is a chronic respiratory disease. See Answer
Prednisolone Oral Solution Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • shortness of breath (even with mild exertion), swelling, rapid weight gain;
  • bruising, thinning skin, or any wound that will not heal;
  • severe depression, changes in personality, unusual thoughts or behavior;
  • new or unusual pain in an arm or leg or in your back;
  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • severe pain in your upper stomach spreading to your back, nausea and vomiting;
  • a seizure (convulsions); or
  • low potassium--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling.

Steroids can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common side effects may include:

  • fluid retention (swelling in your hands or ankles);
  • dizziness, spinning sensation;
  • changes in your menstrual periods;
  • headache;
  • muscle pain or weakness; or
  • stomach discomfort, bloating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Prednisolone Oral Solution (Prednisolone Sodium Phosphate Oral Solution)

SLIDESHOW

What Is Asthma? Symptoms, Causes, and Treatments See Slideshow
Prednisolone Oral Solution Professional Information

SIDE EFFECTS

(listed alphabetically under each subsection):

Cardiovascular: Hypertrophic cardiomyopathy in premature infants.

Dermatologic: Facial erythema; increased sweating; impaired wound healing; may suppress reactions to skin tests; petechiae and ecchymoses; thin fragile skin; urticaria; edema.

Endocrine: Decreased carbohydrate tolerance; development of cushingoid state; hirsutism; increased requirements for insulin or oral hypoglycemic agents in diabetic patients; manifestations of latent diabetes mellitus; menstrual irregularities; secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery or illness; suppression of growth in children.

Fluid and Electrolyte Disturbances: Congestive heart failure in susceptible patients; fluid retention; hypertension; hypokalemic alkalosis; potassium loss; sodium retention.

Gastrointestinal: Abdominal distention; elevation in serum liver enzyme levels (usually reversible upon discontinuation); pancreatitis; peptic ulcer with possible perforation and hemorrhage; ulcerative esophagitis.

Metabolic: Negative nitrogen balance due to protein catabolism.

Musculoskeletal: Aseptic necrosis of femoral and humeral heads; loss of muscle mass; muscle weakness; osteoporosis; pathologic fracture of long bones; steroid myopathy; tendon rupture; vertebral compression fractures.

Neurological: Convulsions; headache; increased intracranial pressure with papilledema (pseudotumor cerebri) usually following discontinuation of treatment; psychic disorders; vertigo.

Ophthalmic: Exophthalmos; glaucoma; increased intraocular pressure; posterior subcapsular cataracts.

Other: Increased appetite; malaise; nausea; weight gain.

Read the entire FDA prescribing information for Prednisolone Oral Solution (Prednisolone Sodium Phosphate Oral Solution)

© Prednisolone Oral Solution Patient Information is supplied by Cerner Multum, Inc. and Prednisolone Oral Solution Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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