Prednisolone

Last updated on RxList: 4/25/2018
Prednisolone Side Effects Center

Medical Editor: John P. Cunha, DO, FACOEP

Last reviewed on RxList 4/25/2018

Prednisolone is an adrenocortical steroid used for multiple conditions including endocrine disorders, rheumatic disorders, collagen diseases, skin diseases, allergies, eye diseases, respiratory diseases, blood disorders, cancers, edematous states, gastrointestinal diseases, and nervous system disorders, among others. The brand name of this medication is discontinued, but generic versions may be available. Common side effects of prednisolone include:

  • infections,
  • heartburn,
  • trouble sleeping (insomnia),
  • hunger,
  • nausea,
  • headache,
  • dizziness,
  • menstrual period changes,
  • increased sweating,
  • acne, and
  • nervousness

The initial dosage of prednisolone varies from 5 mg to 60 mg per day depending on the disease being treated. Prednisolone may interact with other drugs. Tell your doctor all medications and supplements you use. During pregnancy, prednisolone should be used only if prescribed. Consult your doctor before breastfeeding.

Our Prednisolone Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

What Is Asthma? Symptoms, Causes, and Treatments See Slideshow
Prednisolone Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • shortness of breath (even with mild exertion), swelling, rapid weight gain;
  • bruising, thinning skin, or any wound that will not heal;
  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • severe depression, changes in personality, unusual thoughts or behavior;
  • new or unusual pain in an arm or leg or in your back;
  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds;
  • seizure (convulsions); or
  • low potassium--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling.

Steroids can affect growth in children. Tell your doctor if your child is not growing at a normal rate while using this medicine.

Common side effects may include:

  • fluid retention (swelling in your hands or ankles);
  • dizziness, spinning sensation;
  • changes in your menstrual periods;
  • headache;
  • mild muscle pain or weakness; or
  • stomach discomfort, bloating.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Prednisolone (Prednisolone Tablets)

QUESTION

Asthma is a chronic respiratory disease. See Answer
Prednisolone Professional Information

SIDE EFFECTS

Fluid and Electrolyte Disturbances

Sodium retention. Fluid retention. Congestive heart failure in susceptible patients. Potassium loss. Hypokalemic alkalosis. Hypertension.

Musculoskeletal

Muscle weakness. Steroid myopathy. Loss of muscle mass. Osteoporosis. Vertebral compression fractures. Aseptic necrosis of femoral and humeral heads. Pathologic fracture of long bones.

Gastrointestinal

Peptic ulcer with possible perforation and hemorrhage. Pancreatitis. Abdominal distention. Ulcerative esophagitis.

Dermatologic

Impaired wound healing. Thin fragile skin. Petechiae and ecchymoses. Facial erythema. Increased sweating. May suppress reactions to skin tests.

Neurological

Convulsions. Increased intracranial pressure with papilledema (pseudotumor cerebri) usually after treatment. Vertigo. Headache.

Endocrine

Menstrual irregularities. Development of Cushingoid state. Suppression of growth in children. Secondary adrenocortical and pituitary unresponsiveness, particularly in times of stress, as in trauma, surgery, or illness. Decreased carbohydrate tolerance. Manifestations of latent diabetes mellitus. Increased requirements for insulin or oral hypoglycemic agents in diabetics.

Ophthalmic

Posterior subcapsular cataracts. Increased intraocular pressure. Glaucoma. Exophthalmos.

Metabolic

Negative nitrogen balance due to protein catabolism.

Read the entire FDA prescribing information for Prednisolone (Prednisolone Tablets)

© Prednisolone Patient Information is supplied by Cerner Multum, Inc. and Prednisolone Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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