Primacor IV

Medical Editor: John P. Cunha, DO, FACOEP Last updated on RxList: 03/17/2022
Primacor IV Patient Information Including Side Effects

Brand Names: Primacor, Primacor I.V.

Generic Name: milrinone

What is milrinone (Primacor, Primacor I.V.)?

Milrinone is a vasodilator that is used as a short-term treatment for life-threatening heart failure.

Milrinone may also be used for purposes not listed in this medication guide.

What are the possible side effects of milrinone (Primacor, Primacor I.V.)?

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have:

  • chest pain;
  • a light-headed feeling, like you might pass out; or
  • low potassium level--leg cramps, constipation, irregular heartbeats, fluttering in your chest, increased thirst or urination, numbness or tingling, muscle weakness or limp feeling.

Common side effects may include:

  • headache;
  • chest pain; or
  • dizziness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What is the most important information I should know about milrinone (Primacor, Primacor I.V.)?

In an emergency, you may not be able to tell caregivers about your health conditions. Make sure any doctor caring for you afterward knows you received this medicine.


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Primacor IV Patient Information including How Should I Take

What should I discuss with my healthcare provider before I receive milrinone (Primacor, Primacor I.V.)?

You should not be treated with milrinone if you are allergic to it.

If possible before you receive milrinone, tell your doctor if you have ever had:

Tell your doctor if you are pregnant or breastfeeding.

In an emergency, you may not be able to tell caregivers if you are pregnant or breastfeeding. Make sure any doctor caring for your pregnancy or your baby knows you received this medicine.

How is milrinone given (Primacor, Primacor I.V.)?

Milrinone is given as an infusion into a vein, usually around-the-clock for up to 48 hours. A healthcare provider will give you this injection.

Your heart rate and blood pressure will be constantly monitored. Your kidney function and electrolytes may also need to be checked with blood tests.


In the U.S., 1 in every 4 deaths is caused by heart disease. See Answer
Primacor IV Patient Information including If I Miss a Dose

What happens if I miss a dose (Primacor, Primacor I.V.)?

Since milrinone is given by a healthcare professional, you are not likely to miss a dose.

What happens if I overdose (Primacor, Primacor I.V.)?

Since milrinone is given in a medical setting, you will be watched closely to make sure you do not receive too much of this medicine. Your caregivers will quickly treat you if you have overdose symptoms.

What should I avoid after receiving milrinone (Primacor, Primacor I.V.)?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

What other drugs will affect milrinone (Primacor, Primacor I.V.)?

Other drugs may affect milrinone, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Where can I get more information (Primacor, Primacor I.V.)?

Your doctor or pharmacist can provide more information about milrinone.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.


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